Welcome to chemicalbook!
China English Japan Germany
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook Sign in

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> GSK J4 HCl

GSK J4 HCl

GSK J4 HCl price.
  • $110 - $1962
  • Product name: GSK J4 HCl
  • CAS: 1373423-53-0
  • MF: C24H27N5O2
  • MW: 417.5
  • EINECS:
  • MDL Number:MFCD22683852
  • Synonyms:GSK J4;N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-beta-alanine ethyl ester;GSK J4 HCl;N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyriMidinyl]-|-alanine ethyl ester;β-Alanine, N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-, ethyl ester, hydrochloride (1:1);Ethyl 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoate;Ethyl 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)prop;Histone Lysine Demethylase Inhibitor VIII, GSK-J4
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 10mg
  • 50
  • 5mg
  • 25mg
  • 50mg
  • 2x25mg
  • 100mg
  • ManufacturerApexBio Technology
  • Product numberA4190
  • Product descriptionGSKJ4HCl
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4190
  • Product descriptionGSKJ4HCl
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60290
  • Product descriptionGSK-J4 ≥98%
  • Packaging10mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1933
  • Product descriptionGSKJ4 99%
  • Packaging5mg
  • Price$115.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1933
  • Product descriptionGSKJ4 99%
  • Packaging25mg
  • Price$401.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1933
  • Product descriptionGSKJ4 99%
  • Packaging2x25mg
  • Price$616
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3986
  • Product descriptionGSK-J4 99.64%
  • Packaging10mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3986
  • Product descriptionGSK-J4 99.64%
  • Packaging50mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11270115
  • Product descriptionGSK-J4 97%
  • Packaging10mg
  • Price$654
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11270115
  • Product descriptionGSK-J4 97%
  • Packaging50mg
  • Price$1962
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7654
  • Product descriptionGSKJ4HCl >95%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0701
  • Product descriptionGSK-J4 ≥98% (HPLC)
  • Packaging5mg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number420205
  • Product descriptionHistone Lysine Demethylase Inhibitor VIII, GSK-J4
  • Packaging10mg
  • Price$245
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0701
  • Product descriptionGSK-J4 ≥98% (HPLC)
  • Packaging25mg
  • Price$469
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number4594
  • Product descriptionGSKJ4 ≥99%(HPLC)
  • Packaging50
  • Price$876
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberG797555
  • Product descriptionGSKJ4
  • Packaging10mg
  • Price$165
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology A4190 GSKJ4HCl 10mg $110 2021-12-16 Buy
ApexBio Technology A4190 GSKJ4HCl 50mg $350 2021-12-16 Buy
Arctom CFN60290 GSK-J4 ≥98% 10mg $288 2021-12-16 Buy
Axon Medchem Axon1933 GSKJ4 99% 5mg $115.5 2021-12-16 Buy
Axon Medchem Axon1933 GSKJ4 99% 25mg $401.5 2021-12-16 Buy
Axon Medchem Axon1933 GSKJ4 99% 2x25mg $616 2021-12-16 Buy
ChemScene CS-3986 GSK-J4 99.64% 10mg $144 2021-12-16 Buy
ChemScene CS-3986 GSK-J4 99.64% 50mg $420 2021-12-16 Buy
Crysdot CD11270115 GSK-J4 97% 10mg $654 2021-12-16 Buy
Crysdot CD11270115 GSK-J4 97% 50mg $1962 2021-12-16 Buy
DC Chemicals DC7654 GSKJ4HCl >95% 100mg $550 2021-12-16 Buy
Sigma-Aldrich SML0701 GSK-J4 ≥98% (HPLC) 5mg $117 2024-03-01 Buy
Sigma-Aldrich 420205 Histone Lysine Demethylase Inhibitor VIII, GSK-J4 10mg $245 2024-03-01 Buy
Sigma-Aldrich SML0701 GSK-J4 ≥98% (HPLC) 25mg $469 2024-03-01 Buy
Tocris 4594 GSKJ4 ≥99%(HPLC) 50 $876 2021-12-16 Buy
TRC G797555 GSKJ4 10mg $165 2021-12-16 Buy

Properties

Boiling point :581.2±50.0 °C(Predicted)
Density :1.216±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :5.95±0.10(Predicted)
form :Tan semi-solid
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :WBKCKEHGXNWYMO-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

GSK-J4 (1373423-53-0) is a histone demethylase JMJD3/UTX inhibitor. Inhibits demethylation of histone H3K27. Reduces LPS-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 μM for the inhibition of TNFα release). Cell permeable, ethyl ester of GSK J1 (cat.# 10-1393).1 GSK-J4 rescues newborn pups from embryonic lethality in BRAF knockin mice which recapitulate major features of RASopathies.2

More related product prices

2-Cyanopyridine OG-L002 1380288-87-8 JIB-04 GSK 343 BIX 01294 GSK J2 GSK J5 GSK J1 5-Azacytidine RVX-208 Resveratrol TRICHOSTATIN A 864082-47-3 GSK2636771 GSK2982772 BEZ235 (NVP-BEZ235, Dactolisib) GSK 2334470 GSK484 GSK864

Related product price

Suppliers and manufacturers

career henan chemical co
ethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate
$1.00 /1KG
ethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate CAS:1373423-53-0
TargetMol Chemicals Inc.
GSK-J4
$51.00 /2mg
GSK-J4 CAS:1373423-53-0
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Hubei Jusheng Technology Co.,Ltd.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Chemia Biotechnology（Shanghai） Co., Ltd
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem