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ChemicalBook >> CAS DataBase List >> ICA 069673

ICA 069673

ICA 069673 price.
  • $45 - $1529.85
  • Product name: ICA 069673
  • CAS: 582323-16-8
  • MF: C11H6ClF2N3O
  • MW: 269.63
  • EINECS:
  • MDL Number:MFCD20926351
  • Synonyms:ICA 069673;N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide;ICA069673;ICA-069673;Benzamide, N-(2-chloro-5-pyrimidinyl)-3,4-difluoro-;ICA-069673 >=98% (HPLC);Potassium Channel,ICA 069673,ICA-069673,KcsA,inhibit,Inhibitor;N-(2-Chloropyrimidin-5-yl)-3,4-difluorobenzamide
30 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 5
  • 5mg
  • 1mg
  • 25
  • 10MG
  • 25mg
  • 50MG
  • 100mg
  • 250mg
  • 1G
  • ManufacturerAK Scientific
  • Product number5824CR
  • Product descriptionN-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide
  • Packaging25mg
  • Price$502
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010327
  • Product descriptionN-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00%
  • Packaging10MG
  • Price$669.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010327
  • Product descriptionN-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00%
  • Packaging50MG
  • Price$1004.85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010327
  • Product descriptionN-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00%
  • Packaging1G
  • Price$1529.85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7640
  • Product descriptionICA069673
  • Packaging5mg
  • Price$122
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7640
  • Product descriptionICA069673
  • Packaging10mg
  • Price$213
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7640
  • Product descriptionICA069673
  • Packaging25mg
  • Price$449
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7640
  • Product descriptionICA069673
  • Packaging50mg
  • Price$803
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7640
  • Product descriptionICA069673
  • Packaging100mg
  • Price$1433
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22995
  • Product descriptionICA 069673 ≥98%
  • Packaging5mg
  • Price$95
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22995
  • Product descriptionICA 069673 ≥98%
  • Packaging10mg
  • Price$167
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22995
  • Product descriptionICA 069673 ≥98%
  • Packaging25mg
  • Price$363
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22995
  • Product descriptionICA 069673 ≥98%
  • Packaging50mg
  • Price$723
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM253801
  • Product descriptionICA069673 98%
  • Packaging100mg
  • Price$736
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6397
  • Product descriptionICA-069673 99.70%
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6397
  • Product descriptionICA-069673 99.70%
  • Packaging10mg
  • Price$144
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5824CR N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide 25mg $502 2021-12-16 Buy
American Custom Chemicals Corporation API0010327 N-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00% 10MG $669.9 2021-12-16 Buy
American Custom Chemicals Corporation API0010327 N-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00% 50MG $1004.85 2021-12-16 Buy
American Custom Chemicals Corporation API0010327 N-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00% 1G $1529.85 2021-12-16 Buy
ApexBio Technology B7640 ICA069673 5mg $122 2021-12-16 Buy
ApexBio Technology B7640 ICA069673 10mg $213 2021-12-16 Buy
ApexBio Technology B7640 ICA069673 25mg $449 2021-12-16 Buy
ApexBio Technology B7640 ICA069673 50mg $803 2021-12-16 Buy
ApexBio Technology B7640 ICA069673 100mg $1433 2021-12-16 Buy
Cayman Chemical 22995 ICA 069673 ≥98% 5mg $95 2024-03-01 Buy
Cayman Chemical 22995 ICA 069673 ≥98% 10mg $167 2024-03-01 Buy
Cayman Chemical 22995 ICA 069673 ≥98% 25mg $363 2024-03-01 Buy
Cayman Chemical 22995 ICA 069673 ≥98% 50mg $723 2024-03-01 Buy
Chemenu CM253801 ICA069673 98% 100mg $736 2021-12-16 Buy
ChemScene CS-6397 ICA-069673 99.70% 5mg $84 2021-12-16 Buy
ChemScene CS-6397 ICA-069673 99.70% 10mg $144 2021-12-16 Buy

Properties

Boiling point :358.9±37.0 °C(Predicted)
Density :1.539±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DNF:30.0(Max Conc. mg/mL);111.26(Max Conc. mM)
DMSO:36.24(Max Conc. mg/mL);134.4(Max Conc. mM)
Ethanol:30.25(Max Conc. mg/mL);112.18(Max Conc. mM) form :Powder
pka :9.47±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

ICA 069673 is a heteromeric Kv7 channel activator. It is selective for Kv7.2/7.3 over Kv7.3/7.5 (EC50s = 0.69 and 14.3 μM, respectively) and also activates Kv7.4, Kv7.5, and heteromeric Kv7.4/7.5 channels in a dose-dependent manner. ICA 069673 has no activity against hERG, Nav1.5, and Kv7.1 cardiac ion channels (IC50s = >30 μM). Oral administration of ICA 069673 increases latency to first tonic-clonic seizure in the rat maximal electroshock and pentylentetrazol-induced seizure models (ED50s = 1.5 and <1 mg/kg, respectively). Formulations containing ICA 069673 are under clinical investigation for the treatment of epilepsy.