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ChemicalBook >> CAS DataBase List >> Mizoribine

Mizoribine

Mizoribine price.
  • $15 - $1732.5
  • Product name: Mizoribine
  • CAS: 50924-49-7
  • MF: C9H13N3O6
  • MW: 259.22
  • EINECS:637-144-4
  • MDL Number:MFCD00057221
  • Synonyms:N'-[BETA-D-RIBOFURANOSYL]-5-HYDROXYIMIDAZOLE-4-CARBOXAMIDE;MIZORIBINE;4-carbamoyl-1-beta-d-ribofuranosyl-imidazolium-5-olate ;1H-Imidazole-4-carboxamide, 5-hydroxy-1-beta-D-ribofuranosyl-;Anhydro-4-carbamoyl-5-hydroxy-1-b-D-ribofuranosyl-imidazolium-hydroxide;Brn 4151713;Mizoribina;Bredinin (Mizoribine)
48 prices
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  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
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Package
  • 5mg
  • 10mg
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  • 0.1g
  • 100mg
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  • 1g
  • 5g
  • ManufacturerAHH
  • Product numberMT-54312
  • Product descriptionMizoribine 98%
  • Packaging0.1g
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberQ571
  • Product descriptionMizoribine
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberQ571
  • Product descriptionMizoribine
  • Packaging100mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA306960
  • Product description1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide 98+%
  • Packaging5mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA306960
  • Product description1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide 98+%
  • Packaging10mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA306960
  • Product description1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide 98+%
  • Packaging50mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA306960
  • Product description1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide 98+%
  • Packaging5g
  • Price$1139
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003412
  • Product descriptionMIZORIBINE 95.00%
  • Packaging10MG
  • Price$179.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003412
  • Product descriptionMIZORIBINE 95.00%
  • Packaging100MG
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1472
  • Product descriptionMizoribine
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1472
  • Product descriptionMizoribine
  • Packaging25mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1472
  • Product descriptionMizoribine
  • Packaging50mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1472
  • Product descriptionMizoribine
  • Packaging100mg
  • Price$315
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS023268
  • Product descriptionMizoribine ≥98%
  • Packaging5mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS023268
  • Product descriptionMizoribine ≥98%
  • Packaging10mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS023268
  • Product descriptionMizoribine ≥98%
  • Packaging50mg
  • Price$34
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-54312 Mizoribine 98% 0.1g $250 2021-12-16 Buy
AK Scientific Q571 Mizoribine 10mg $39 2021-12-16 Buy
AK Scientific Q571 Mizoribine 100mg $218 2021-12-16 Buy
Ambeed A306960 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide 98+% 5mg $15 2021-12-16 Buy
Ambeed A306960 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide 98+% 10mg $20 2021-12-16 Buy
Ambeed A306960 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide 98+% 50mg $34 2021-12-16 Buy
Ambeed A306960 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide 98+% 5g $1139 2021-12-16 Buy
American Custom Chemicals Corporation API0003412 MIZORIBINE 95.00% 10MG $179.55 2021-12-16 Buy
American Custom Chemicals Corporation API0003412 MIZORIBINE 95.00% 100MG $1732.5 2021-12-16 Buy
ApexBio Technology B1472 Mizoribine 10mg $70 2021-12-16 Buy
ApexBio Technology B1472 Mizoribine 25mg $140 2021-12-16 Buy
ApexBio Technology B1472 Mizoribine 50mg $210 2021-12-16 Buy
ApexBio Technology B1472 Mizoribine 100mg $315 2021-12-16 Buy
Arctom AS023268 Mizoribine ≥98% 5mg $15 2021-12-16 Buy
Arctom AS023268 Mizoribine ≥98% 10mg $20 2021-12-16 Buy
Arctom AS023268 Mizoribine ≥98% 50mg $34 2021-12-16 Buy

Properties

Melting point :>2000C
alpha :D27 -35° (c = 0.8 in H2O)
Boiling point :402.47°C (rough estimate)
Density :1.4155 (rough estimate)
refractive index :1.5100 (estimate)
storage temp. :2-8°C
solubility :DMSO (Slightly), Water (Slightly)
form :Solid
pka :6.75(at 25℃)
color :White to Off-White
λmax :280nm(lit.)
Merck :14,6222
InChIKey :HZQDCMWJEBCWBR-UUOKFMHZSA-N
CAS DataBase Reference :50924-49-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Mizoribine Hydrobromide is an imidazole nucleoside immunosuppressant agent that was first isolated from the mold Eupenicillium brefeldimium with antibiotic and cytotoxic effects. In a mouse model for IgA nephropathy, Mizoribine Hydrobromide was documented to influence the proliferation of B cells and decrease the glomerular IgA load while increasing glomerular expansion. In addition in human B cells the compound has been observed to Inhibit the expression of cyclin A. The immunosuppressive effects of Mizoribine Hydrobromide also effects T cells through suppression of G to S phase transition. In the case of puromycin aminonucleoside nephropathy Mizoribine Hydrobromide demonstrated the ability to prevent podocyte injury. The compound has also been documented to induce the differentiation of promyelocytes on a mechansim relying on impaired guanine nucleotide synthesis.

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