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ChemicalBook >> CAS DataBase List >> PF-04620110

PF-04620110

PF-04620110 price.
  • $71 - $4966.5
  • Product name: PF-04620110
  • CAS: 1109276-89-2
  • MF: C21H24N4O4
  • MW: 396.44
  • EINECS:
  • MDL Number:MFCD19443642
  • Synonyms:Cyclohexaneacetic acid, 4-[4-(4-amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-, trans-;2-((1r,4r)-4-(4-(4-aMino-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetic acid;2-(4-(4-(4-aMiNA-5-oxo-7,8-dihydropyriMido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetic acid;2-(trans-4-(4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f]-[1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl);2-(trans-4-(4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetic acid;2-[4-[4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetic acid;2-(trans-4-(4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f]-[1,4]oxazepin-6(5H)-yl)phenyl)cyclohex;PF-04620110
Price29 Properties Safety Information Description
29 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 10mg
  • 25mg
  • 50mg
  • 5
  • 5MG
  • 25
  • 2.5mg
  • 1g
  • 1000mg
  • 5G
  • 100mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number2009AA
  • Product description2-(trans-4-(4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)aceticacid
  • Packaging250mg
  • Price$1051
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2009AA
  • Product description2-(trans-4-(4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)aceticacid
  • Packaging1g
  • Price$2273
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0014060
  • Product descriptionPF-04620110 95.00%
  • Packaging5MG
  • Price$205.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0014060
  • Product descriptionPF-04620110 95.00%
  • Packaging5G
  • Price$4966.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4384
  • Product descriptionPF-04620110
  • Packaging10mM(in 1mL DMSO)
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4384
  • Product descriptionPF-04620110
  • Packaging50mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181082
  • Product descriptionPF-04620110 >98%
  • Packaging100mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181082
  • Product descriptionPF-04620110 >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181082
  • Product descriptionPF-04620110 >98%
  • Packaging1000mg
  • Price$2839
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16425
  • Product descriptionPF-04620110 ≥98%
  • Packaging5mg
  • Price$92
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16425
  • Product descriptionPF-04620110 ≥98%
  • Packaging10mg
  • Price$155
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16425
  • Product descriptionPF-04620110 ≥98%
  • Packaging25mg
  • Price$360
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0370
  • Product descriptionPF-04620110 99.30%
  • Packaging5mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0370
  • Product descriptionPF-04620110 99.30%
  • Packaging10mg
  • Price$131
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0370
  • Product descriptionPF-04620110 99.30%
  • Packaging50mg
  • Price$432
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0370
  • Product descriptionPF-04620110 99.30%
  • Packaging100mg
  • Price$780
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2009AA 2-(trans-4-(4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)aceticacid 250mg $1051 2021-12-16 Buy
AK Scientific 2009AA 2-(trans-4-(4-(4-Amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)aceticacid 1g $2273 2021-12-16 Buy
American Custom Chemicals Corporation API0014060 PF-04620110 95.00% 5MG $205.7 2021-12-16 Buy
American Custom Chemicals Corporation API0014060 PF-04620110 95.00% 5G $4966.5 2021-12-16 Buy
ApexBio Technology A4384 PF-04620110 10mM(in 1mL DMSO) $120 2021-12-16 Buy
ApexBio Technology A4384 PF-04620110 50mg $380 2021-12-16 Buy
Biorbyt Ltd orb181082 PF-04620110 >98% 100mg $765 2021-12-16 Buy
Biorbyt Ltd orb181082 PF-04620110 >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb181082 PF-04620110 >98% 1000mg $2839 2021-12-16 Buy
Cayman Chemical 16425 PF-04620110 ≥98% 5mg $92 2024-03-01 Buy
Cayman Chemical 16425 PF-04620110 ≥98% 10mg $155 2024-03-01 Buy
Cayman Chemical 16425 PF-04620110 ≥98% 25mg $360 2024-03-01 Buy
ChemScene CS-0370 PF-04620110 99.30% 5mg $72 2021-12-16 Buy
ChemScene CS-0370 PF-04620110 99.30% 10mg $131 2021-12-16 Buy
ChemScene CS-0370 PF-04620110 99.30% 50mg $432 2021-12-16 Buy
ChemScene CS-0370 PF-04620110 99.30% 100mg $780 2021-12-16 Buy
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Properties

Boiling point :701.9±60.0 °C(Predicted)
Density :1.326
storage temp. :room temp
solubility :DMSO: soluble10mg/mL (clear solution)
pka :4.72±0.10(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Acyl-CoA:diacylglycerol acyltransferase-1 (DGAT-1) catalyzes the final committed step in the biosynthesis of triglycerides and has potential roles in obesity, diabetes, and atherosclerosis. PF-04620110 is a potent inhibitor of DGAT-1 (IC50 = 19 nM) that is without effect on DGAT-2. It has high oral bioavailability (100%) in rats, with a moderate half-life of 6.8 hours. PF-04620110 significantly blocks an increase in plasma triglyceride levels following a corn oil bolus in rats.

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Suppliers and manufacturers

career henan chemical co
PF-04620110
$2.00 /1kg
PF-04620110 CAS:1109276-89-2
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
InvivoChem
TargetMol Chemicals Inc.
Aladdin Scientific
Amadis Chemical Company Limited
Mainchem Co., Ltd.