PPQ-102
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- $48 - $1600
- Product name: PPQ-102
- CAS: 931706-15-9
- MF: C26H22N4O3
- MW: 438.48
- EINECS:
- MDL Number:MFCD14824240
- Synonyms:PPQ-102;7,9-DIMETHYL-6-(5-METHYL-2-FURYL)-11-PHENYL-6,7-DIHYDROPYRIMIDO[4 ',5':3,4]PYRROLO[1,2-A]QUINOXALINE-8,10(5H,9H)-DIONE;PPQ-102, CFTR Inhibitor;6,7-Dihydro-7,9-dimethyl-6-(5-methyl-2-furanyl)-11-phenylpyrimido[4',5':3,4]pyrrolo[1,2-a]quinoxaline-8,10(5H,9)-dione;7,9-Dimethyl-6-(5-methylfuran-2-yl)-11-phenyl-5,6-dihydropyrimido[4',5':3,4]pyrrolo[1,2-a]quin;6,7-Dihydro-7,9-dimethyl-6-(5-methyl-2-furanyl)-11-phenylpyrimido[4',5':3,4]pyrrolo[1,2-a]quinoxaline-8,10(5H,9)-dione PPQ-102;PPQ-102 6,7-Dihydro-7,9-dimethyl-6-(5-methyl-2-furanyl)-11-phenylpyrimido[4',5':3,4]pyrrolo[1,2-a]quinoxaline-8,10(5H,9)-dione;PPQ 102, >=98%
29 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 50
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number3977AH
- Product description7,9-Dimethyl-6-(5-methyl-furan-2-yl)-11-phenyl-6,7-dihydro-5H-5,7,9,11a-tetraaza-benzo[a]fluorene-8,10-dione
- Packaging25mg
- Price$304
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA621408
- Product descriptionPPQ-102 98+%
- Packaging5mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA621408
- Product descriptionPPQ-102 98+%
- Packaging10mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA621408
- Product descriptionPPQ-102 98+%
- Packaging25mg
- Price$199
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA621408
- Product descriptionPPQ-102 98+%
- Packaging50mg
- Price$258
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA621408
- Product descriptionPPQ-102 98+%
- Packaging100mg
- Price$335
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0014078
- Product descriptionPPQ-102 95.00%
- Packaging5MG
- Price$204.6
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3504
- Product descriptionPPQ-102
- Packaging5mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3504
- Product descriptionPPQ-102
- Packaging10mg
- Price$245
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3504
- Product descriptionPPQ-102
- Packaging50mg
- Price$961
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3504
- Product descriptionPPQ-102
- Packaging100mg
- Price$1496
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16275
- Product descriptionPPQ-102 ≥95%
- Packaging5mg
- Price$90
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16275
- Product descriptionPPQ-102 ≥95%
- Packaging10mg
- Price$171
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16275
- Product descriptionPPQ-102 ≥95%
- Packaging50mg
- Price$710
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-2863
- Product descriptionPPQ-102 99.82%
- Packaging5mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-2863
- Product descriptionPPQ-102 99.82%
- Packaging10mg
- Price$168
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3977AH | 7,9-Dimethyl-6-(5-methyl-furan-2-yl)-11-phenyl-6,7-dihydro-5H-5,7,9,11a-tetraaza-benzo[a]fluorene-8,10-dione | 25mg | $304 | 2021-12-16 | Buy |
| Ambeed | A621408 | PPQ-102 98+% | 5mg | $59 | 2021-12-16 | Buy |
| Ambeed | A621408 | PPQ-102 98+% | 10mg | $99 | 2021-12-16 | Buy |
| Ambeed | A621408 | PPQ-102 98+% | 25mg | $199 | 2021-12-16 | Buy |
| Ambeed | A621408 | PPQ-102 98+% | 50mg | $258 | 2021-12-16 | Buy |
| Ambeed | A621408 | PPQ-102 98+% | 100mg | $335 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0014078 | PPQ-102 95.00% | 5MG | $204.6 | 2021-12-16 | Buy |
| ApexBio Technology | B3504 | PPQ-102 | 5mg | $142 | 2021-12-16 | Buy |
| ApexBio Technology | B3504 | PPQ-102 | 10mg | $245 | 2021-12-16 | Buy |
| ApexBio Technology | B3504 | PPQ-102 | 50mg | $961 | 2021-12-16 | Buy |
| ApexBio Technology | B3504 | PPQ-102 | 100mg | $1496 | 2021-12-16 | Buy |
| Cayman Chemical | 16275 | PPQ-102 ≥95% | 5mg | $90 | 2024-03-01 | Buy |
| Cayman Chemical | 16275 | PPQ-102 ≥95% | 10mg | $171 | 2024-03-01 | Buy |
| Cayman Chemical | 16275 | PPQ-102 ≥95% | 50mg | $710 | 2024-03-01 | Buy |
| ChemScene | CS-2863 | PPQ-102 99.82% | 5mg | $96 | 2021-12-16 | Buy |
| ChemScene | CS-2863 | PPQ-102 99.82% | 10mg | $168 | 2021-12-16 | Buy |
Properties
Melting point :>300℃ (ethanol )
Boiling point :648.7±65.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :-20C
solubility :DMF: 0.2 mg/ml
form :White crystalline solid
pka :1.00±0.40(Predicted)
color :Light yellow to yellow
Boiling point :648.7±65.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :-20C
solubility :DMF: 0.2 mg/ml
form :White crystalline solid
pka :1.00±0.40(Predicted)
color :Light yellow to yellow
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR). PPQ-102 is a cell-permeable pyrimido-pyrrolo-quinoxalinedione that reversibly inhibits CFTR chloride channels with an IC50 value of 90 nM. At 0.5-5 μM, PPQ-102 has been used to reduce the size and number of renal cysts in a neonatal kidney organ culture model of polycystic kidney disease. At 1 μM, PPQ-102 can increase vascular endothelial growth factor-A production in cultured airway epithelial NCI-H292 cells, triggering epidermal growth factor receptor phosphorylation.More related product prices
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