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ChemicalBook >> CAS DataBase List >> SU 6668

SU 6668

SU 6668 price.
  • $5 - $1350
  • Product name: SU 6668
  • CAS: 210644-62-5
  • MF: C18H18N2O3
  • MW: 310.35
  • EINECS:
  • MDL Number:MFCD09743433
  • Synonyms:SU 6668;3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)-propionic acid;1H-Pyrrole-3-propanoic acid, 5-((Z)-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-;5-((Z)-1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-propanoic acid;PDGFR Tyrosine Kinase Inhibitor VI, SU6668;3-[2,4-dimethyl-5-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoicacid;PDGFR Tyrosine Kinase Inhibitor VI, SU6668 - CAS 210644-62-5 - Calbiochem;3-(2,4-Dimethyl-5-{[(3Z)-2-oxo-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid
16 prices
Selected condition:
Brand
  • Ambeed
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mg
  • 25mg
  • 5mg
  • 10
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • ManufacturerAmbeed
  • Product numberA146183
  • Product descriptionSU6668 97%
  • Packaging25mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA146183
  • Product descriptionSU6668 97%
  • Packaging5g
  • Price$405
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM147636
  • Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 95%+
  • Packaging1g
  • Price$491
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0102969
  • Product description(Z)-Orantinib 99.02%
  • Packaging10mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0102969
  • Product description(Z)-Orantinib 99.02%
  • Packaging50mg
  • Price$432
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0102969
  • Product description(Z)-Orantinib 99.02%
  • Packaging100mg
  • Price$756
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11166850
  • Product descriptionSU6668 97%
  • Packaging250mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11166850
  • Product descriptionSU6668 97%
  • Packaging1g
  • Price$547
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN20031
  • Product descriptionSU6668
  • Packaging25mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN20031
  • Product descriptionSU6668
  • Packaging250mg
  • Price$209
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number132613
  • Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 97%
  • Packaging250mg
  • Price$537
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number132613
  • Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 97%
  • Packaging1g
  • Price$1350
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberCDS023028
  • Product description2,4-Dimethyl-5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-pyrrole-3-propanoic acid
  • Packaging100MG
  • Price$308
  • Updated2023-01-07
  • Buy
  • ManufacturerTocris
  • Product number3335
  • Product descriptionSU6668 ≥99%(HPLC)
  • Packaging10
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberD457088
  • Product description(Z)​-​3-​(2,​4-​Dimethyl-​5-​((2-​oxoindolin-​3-​ylidene)​methyl)​-​1H-​pyrrol-​3-​yl)​propanoicacid(SU-6668)
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256776
  • Product descriptionSU 6668
  • Packaging10mg
  • Price$466
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A146183 SU6668 97% 25mg $5 2021-12-16 Buy
Ambeed A146183 SU6668 97% 5g $405 2021-12-16 Buy
Chemenu CM147636 (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 95%+ 1g $491 2021-12-16 Buy
ChemScene CS-0102969 (Z)-Orantinib 99.02% 10mg $108 2021-12-16 Buy
ChemScene CS-0102969 (Z)-Orantinib 99.02% 50mg $432 2021-12-16 Buy
ChemScene CS-0102969 (Z)-Orantinib 99.02% 100mg $756 2021-12-16 Buy
Crysdot CD11166850 SU6668 97% 250mg $218 2021-12-16 Buy
Crysdot CD11166850 SU6668 97% 1g $547 2021-12-16 Buy
CSNpharm CSN20031 SU6668 25mg $56 2021-12-16 Buy
CSNpharm CSN20031 SU6668 250mg $209 2021-12-16 Buy
Matrix Scientific 132613 (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 97% 250mg $537 2021-12-16 Buy
Matrix Scientific 132613 (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 97% 1g $1350 2021-12-16 Buy
Sigma-Aldrich CDS023028 2,4-Dimethyl-5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-pyrrole-3-propanoic acid 100MG $308 2023-01-07 Buy
Tocris 3335 SU6668 ≥99%(HPLC) 10 $208 2021-12-16 Buy
TRC D457088 (Z)​-​3-​(2,​4-​Dimethyl-​5-​((2-​oxoindolin-​3-​ylidene)​methyl)​-​1H-​pyrrol-​3-​yl)​propanoicacid(SU-6668) 5mg $90 2021-12-16 Buy
Usbiological 256776 SU 6668 10mg $466 2021-12-16 Buy

Properties

storage temp. :+2C to +8C
solubility :DMSO : 50 mg/mL (161.11 mM; Need ultrasonic)
form :Dark yellow solid
color :Orange to red

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

PDGFR Tyrosine Kinase Inhibitor VI, SU6668 is a cell-permeable indolinone compound that acts as a potent ATP-competitive inhibitor against RTKs (receptor tyrosine kinases) Kit, PDGFRβ, VEGFR2 (Flk-1/KDR), FGFR1 activity in vitro (IC50 = 0.01, 0.1, 3.9, and 3.8 M, respectively) and PDGF/VEGF/bFGF-mediated angiogenesis and tumor development. Although initially characterized as an RTK inhibitor, SU6668 is now also known to target ser/thr kinases Aurora A, Aurora B, TBK1 (NAK/T2K), and AMPK (IC50 = 0.85, 0.047, 1.4, and 1.8 M, respectively), as well as non-receptor TKs Lyn and Yes (IC50 = 4.3 and 5.8 M, respectively).

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