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ChemicalBook >> CAS DataBase List >> Tubacin

Tubacin

$75 - $2986.9
Product name: Tubacin
CAS: 537049-40-4
MF: C41H43N3O7S
MW: 721.86
EINECS:
MDL Number:MFCD18452824
Synonyms:Tubacin;N1-(4-((2R,4R,6S)-4-((4,5-diphenyloxazol-2-ylthio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide;N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide Tubacin;N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide;Tubacin, >=98%;N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-di;BML-GR362;Tubacin (BML-GR362)

Price23 Properties Safety Information Description

23 prices

Selected condition：

Brand

AK Scientific
ApexBio Technology
Arctom
Biorbyt Ltd
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Medical Isotopes, Inc.
Sigma-Aldrich
Tocris
TRC
Usbiological

Package

500ug
1mg
2.5mg
5mg
10mg
20mg
1
25mg
100mg

ManufacturerAK Scientific
Product number2275AH
Product descriptionTubacinhydrate
Packaging25mg
Price$1384
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4501
Product descriptionTubacin
Packaging1mg
Price$75
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4501
Product descriptionTubacin
Packaging5mg
Price$250
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4501
Product descriptionTubacin
Packaging10mg
Price$470
Updated2021-12-16
Buy

ManufacturerArctom
Product numberCFN60354
Product descriptionTubacin ≥98%
Packaging5mg
Price$593
Updated2021-12-16
Buy

ManufacturerBiorbyt Ltd
Product numberorb146282
Product descriptionTubacin (BML-GR362) >98%
Packaging100mg
Price$2986.9
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number13691
Product descriptionTubacin ≥90%
Packaging1mg
Price$106
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number13691
Product descriptionTubacin ≥90%
Packaging5mg
Price$336
Updated2024-03-01
Buy

ManufacturerChemScene
Product numberCS-5738
Product descriptionTubacin 99.17%
Packaging1mg
Price$96
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-5738
Product descriptionTubacin 99.17%
Packaging5mg
Price$324
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-5738
Product descriptionTubacin 99.17%
Packaging10mg
Price$612
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-5738
Product descriptionTubacin 99.17%
Packaging20mg
Price$1164
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD11108880
Product descriptionTubacin 95+%
Packaging5mg
Price$290
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD11108880
Product descriptionTubacin 95+%
Packaging10mg
Price$540
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD11108880
Product descriptionTubacin 95+%
Packaging25mg
Price$1030
Updated2021-12-16
Buy

ManufacturerDC Chemicals
Product numberDC5178
Product descriptionTubacin(BML-GR362) >98%
Packaging100mg
Price$2000
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	2275AH	Tubacinhydrate	25mg	$1384	2021-12-16	Buy
ApexBio Technology	A4501	Tubacin	1mg	$75	2021-12-16	Buy
ApexBio Technology	A4501	Tubacin	5mg	$250	2021-12-16	Buy
ApexBio Technology	A4501	Tubacin	10mg	$470	2021-12-16	Buy
Arctom	CFN60354	Tubacin ≥98%	5mg	$593	2021-12-16	Buy
Biorbyt Ltd	orb146282	Tubacin (BML-GR362) >98%	100mg	$2986.9	2021-12-16	Buy
Cayman Chemical	13691	Tubacin ≥90%	1mg	$106	2024-03-01	Buy
Cayman Chemical	13691	Tubacin ≥90%	5mg	$336	2024-03-01	Buy
ChemScene	CS-5738	Tubacin 99.17%	1mg	$96	2021-12-16	Buy
ChemScene	CS-5738	Tubacin 99.17%	5mg	$324	2021-12-16	Buy
ChemScene	CS-5738	Tubacin 99.17%	10mg	$612	2021-12-16	Buy
ChemScene	CS-5738	Tubacin 99.17%	20mg	$1164	2021-12-16	Buy
Crysdot	CD11108880	Tubacin 95+%	5mg	$290	2021-12-16	Buy
Crysdot	CD11108880	Tubacin 95+%	10mg	$540	2021-12-16	Buy
Crysdot	CD11108880	Tubacin 95+%	25mg	$1030	2021-12-16	Buy
DC Chemicals	DC5178	Tubacin(BML-GR362) >98%	100mg	$2000	2021-12-16	Buy

Next Last

Properties

Melting point :155 - 157°C
storage temp. :-20°C
solubility :DMSO: ≥10mg/mL
form :powder
color :white to tan

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501

Precautionary statements:

P280	Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Tubacin is a tubulin acetylation inducer that selectively inhibits histone deacetylase (HDAC) 6 (IC50 = 4 nM). In comparison, it demonstrates at least 300-fold selectivity against all other HDAC isoforms (IC50s range from 1.3-17.3 μM). Tubacin induces α-tubulin hyperacetylation at 2.5 μM in primary cortical neuron cultures. Tubacin inhibition of HDAC6 has been used as a biochemical tool to control microtubule-dependent intracellular trafficking, to manipulate the aggresome formation of misfolded proteins in certain diseases, and to study the dynamics of cellular adhesion.

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