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ChemicalBook >> CAS DataBase List >> SPLITOMICIN

SPLITOMICIN

SPLITOMICIN price.
  • $25 - $824
  • Product name: SPLITOMICIN
  • CAS: 5690-03-9
  • MF: C13H10O2
  • MW: 198.22
  • EINECS:
  • MDL Number:MFCD08705254
  • Synonyms:SPLITOMICIN;1,2-DIHYDRO-3H-NAPHTHO[2,1-B]PYRAN-3-ONE;2-Hydroxy-1-naphthalenepropanoic acid delta-lactone;Splitomycin;1H-Benzo[f]chromen-3(2H)-one;Splitomicin >Spitomicin;1,2-Dihydro-3H-benzo[f]chromen-3-one
32 prices
Selected condition:
Brand
  • Activate Scientific
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • 1mg
  • 5mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 200mg
  • ManufacturerActivate Scientific
  • Product numberAS146495
  • Product descriptionSplitomicin 95%
  • Packaging1g
  • Price$308
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0088-M001
  • Product descriptionSplitomicin ≥98%(NMR)
  • Packaging1mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0088-M005
  • Product descriptionSplitomicin ≥98%(NMR)
  • Packaging5mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2049AH
  • Product descriptionSplitomicin
  • Packaging200mg
  • Price$276
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2049AH
  • Product descriptionSplitomicin
  • Packaging1g
  • Price$824
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8242
  • Product descriptionSplitomicin
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8242
  • Product descriptionSplitomicin
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8242
  • Product descriptionSplitomicin
  • Packaging50mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13168
  • Product descriptionSplitomicin ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13168
  • Product descriptionSplitomicin ≥98%
  • Packaging5mg
  • Price$63
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13168
  • Product descriptionSplitomicin ≥98%
  • Packaging10mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13168
  • Product descriptionSplitomicin ≥98%
  • Packaging25mg
  • Price$267
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019737
  • Product descriptionSplitomicin 98.42%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019737
  • Product descriptionSplitomicin 98.42%
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019737
  • Product descriptionSplitomicin 98.42%
  • Packaging25mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019737
  • Product descriptionSplitomicin 98.42%
  • Packaging50mg
  • Price$220
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS146495 Splitomicin 95% 1g $308 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-0088-M001 Splitomicin ≥98%(NMR) 1mg $25 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-0088-M005 Splitomicin ≥98%(NMR) 5mg $45 2021-12-16 Buy
AK Scientific 2049AH Splitomicin 200mg $276 2021-12-16 Buy
AK Scientific 2049AH Splitomicin 1g $824 2021-12-16 Buy
ApexBio Technology A8242 Splitomicin 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology A8242 Splitomicin 10mg $70 2021-12-16 Buy
ApexBio Technology A8242 Splitomicin 50mg $240 2021-12-16 Buy
Cayman Chemical 13168 Splitomicin ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 13168 Splitomicin ≥98% 5mg $63 2024-03-01 Buy
Cayman Chemical 13168 Splitomicin ≥98% 10mg $109 2024-03-01 Buy
Cayman Chemical 13168 Splitomicin ≥98% 25mg $267 2024-03-01 Buy
ChemScene CS-0019737 Splitomicin 98.42% 5mg $50 2021-12-16 Buy
ChemScene CS-0019737 Splitomicin 98.42% 10mg $70 2021-12-16 Buy
ChemScene CS-0019737 Splitomicin 98.42% 25mg $140 2021-12-16 Buy
ChemScene CS-0019737 Splitomicin 98.42% 50mg $220 2021-12-16 Buy

Properties

Melting point :73-74.5℃
storage temp. :2-8°C
solubility :insoluble in H2O; ≥44.2 mg/mL in EtOH with ultrasonic; ≥9.05 mg/mL in DMSO
form :solid
color :White to Almost white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Sir2p, the product of the SIR2 gene, is a conserved NAD+-dependent histone deacetylase (HDAC) involved in the regulation of the lifespan in yeast. It plays roles in silencing gene expression and negatively regulates the initiation of DNA replication. Splitomicin is a small molecule inhibitor of Sir2p histone deacetylase activity, displaying higher activity in vivo (minimal inhibitory concentration = 0.49 μM) than in vitro (IC50 = 60 μM). It less effectively inhibits yeast Hst1, a paralog of Sir2p. Splitomicin has diverse effects on mammalian cells.

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