VU0456810
- $36 - $1800
- Product name: VU0456810
- CAS: 1443246-62-5
- MF: C17H14F2N4O
- MW: 328.32
- EINECS:
- MDL Number:MFCD27977571
- Synonyms:1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea;CID 56642816;ML297;VU0456810;1-(3,4-DIFLUOROPHENYL)-3-(5-METHYL-2-PHENYLPYRAZOL-3-YL)UREA;ML297, Pubchem: CID 56642816;ML297 (VU0456810);ML 297;ML-297;ML297;VU0456810;VU-0456810;VU 0456810
28 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 50
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5464
- Product descriptionML297
- Packaging50mg
- Price$547
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1209586
- Product description1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea 97%
- Packaging5mg
- Price$36
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1209586
- Product description1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea 97%
- Packaging10mg
- Price$53
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1209586
- Product description1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea 97%
- Packaging25mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1209586
- Product description1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea 97%
- Packaging50mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1209586
- Product description1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea 97%
- Packaging250mg
- Price$334
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5045
- Product descriptionML-297
- Packaging10mg
- Price$234
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5045
- Product descriptionML-297
- Packaging50mg
- Price$985
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14792
- Product descriptionML-297 ≥98%
- Packaging1mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14792
- Product descriptionML-297 ≥98%
- Packaging5mg
- Price$216
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14792
- Product descriptionML-297 ≥98%
- Packaging10mg
- Price$380
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14792
- Product descriptionML-297 ≥98%
- Packaging25mg
- Price$830
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0033056
- Product descriptionML297 98.70%
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0033056
- Product descriptionML297 98.70%
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0033056
- Product descriptionML297 98.70%
- Packaging25mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0033056
- Product descriptionML297 98.70%
- Packaging50mg
- Price$420
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | SYN5464 | ML297 | 50mg | $547 | 2021-12-16 | Buy |
Ambeed | A1209586 | 1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea 97% | 5mg | $36 | 2021-12-16 | Buy |
Ambeed | A1209586 | 1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea 97% | 10mg | $53 | 2021-12-16 | Buy |
Ambeed | A1209586 | 1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea 97% | 25mg | $90 | 2021-12-16 | Buy |
Ambeed | A1209586 | 1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea 97% | 50mg | $135 | 2021-12-16 | Buy |
Ambeed | A1209586 | 1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea 97% | 250mg | $334 | 2021-12-16 | Buy |
ApexBio Technology | C5045 | ML-297 | 10mg | $234 | 2021-12-16 | Buy |
ApexBio Technology | C5045 | ML-297 | 50mg | $985 | 2021-12-16 | Buy |
Cayman Chemical | 14792 | ML-297 ≥98% | 1mg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 14792 | ML-297 ≥98% | 5mg | $216 | 2024-03-01 | Buy |
Cayman Chemical | 14792 | ML-297 ≥98% | 10mg | $380 | 2024-03-01 | Buy |
Cayman Chemical | 14792 | ML-297 ≥98% | 25mg | $830 | 2024-03-01 | Buy |
ChemScene | CS-0033056 | ML297 98.70% | 5mg | $90 | 2021-12-16 | Buy |
ChemScene | CS-0033056 | ML297 98.70% | 10mg | $150 | 2021-12-16 | Buy |
ChemScene | CS-0033056 | ML297 98.70% | 25mg | $280 | 2021-12-16 | Buy |
ChemScene | CS-0033056 | ML297 98.70% | 50mg | $420 | 2021-12-16 | Buy |
Properties
Boiling point :377.8±42.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble15mg/mL, clear
pka :12.54±0.70(Predicted)
form :White powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble15mg/mL, clear
pka :12.54±0.70(Predicted)
form :White powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
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Signal word: | Warning | ||||||||||||||
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Precautionary statements: |
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Description
G protein-regulated inwardly rectifying potassium (GIRK1-4) channels are a family of Kir3.1-Kir3.4 ion channels that modulate cell excitability. The four different GIRK subunits are composed in different homo- and heterotetrameric combinations, which are expressed with regional specificity throughout the central nervous system and in the periphery. ML-297 is a selective GIRK1/2 activator (EC50s = 0.16 and 1.8 μM for GIRK1/2 and GIRK1/4, respectively, and is completely inactive at GIRK2/3). In two different mouse models of epilepsy, ML-297 at 60 mg/kg was shown to delay seizure onset and to prevent convulsions.More related product prices
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