XL019
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- $48 - $3980
- Product name: XL019
- CAS: 945755-56-6
- MF: C25H28N6O2
- MW: 444.53
- EINECS:-0
- MDL Number:MFCD24386874
- Synonyms:2S)-N-[4-[2-[[4-(4-Morpholinyl)phenyl]amino]-4-pyrimidinyl]phenyl]-2-pyrrolidinecarboxamide XL019;XL019 2-Pyrrolidinecarboxamide, N-[4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]phenyl]-, (2S)-;Pyrrolidine-2-carboxylic acid {4-[2-(4-morpholin-4-yl-phenylamino)-pyrimidin-4-yl]-phenyl}-amide;XL019, >=98%;XL019;XL019/XL-019;(2S)-N-[4-[2-[[4-(4-Morpholinyl)phenyl]amino]-4-pyrimidinyl]phenyl]-2-pyrrolidinecarboxamide;(S)-N-(4-(2-(4-MORPHOLINOPHENYLAMINO)PYRIMIDIN-4-YL)PHENYL)PYRROLIDINE-2-CARBOXAMIDE
36 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1MG
- 2mg
- 5mg
- 2x5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2807AH
- Product description(2S)-N-[4-[2-[[4-(4-Morpholinyl)phenyl]amino]-4-pyrimidinyl]phenyl]-2-pyrrolidinecarboxamide
- Packaging5mg
- Price$193
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403201
- Product descriptionXL019 98+%
- Packaging2mg
- Price$48
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403201
- Product descriptionXL019 98+%
- Packaging5mg
- Price$62
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403201
- Product descriptionXL019 98+%
- Packaging10mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403201
- Product descriptionXL019 98+%
- Packaging25mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403201
- Product descriptionXL019 98+%
- Packaging50mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403201
- Product descriptionXL019 98+%
- Packaging100mg
- Price$176
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403201
- Product descriptionXL019 98+%
- Packaging250mg
- Price$351
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403201
- Product descriptionXL019 98+%
- Packaging1g
- Price$876
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024547
- Product descriptionXL-019 95.00%
- Packaging1MG
- Price$340.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024547
- Product descriptionXL-019 95.00%
- Packaging5MG
- Price$496.95
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3937
- Product descriptionXL019
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3937
- Product descriptionXL019
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2231
- Product descriptionXL019 99%
- Packaging2x5mg
- Price$176
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2231
- Product descriptionXL019 99%
- Packaging25mg
- Price$385
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146222
- Product descriptionXL019 >98%
- Packaging100mg
- Price$838.1
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2807AH | (2S)-N-[4-[2-[[4-(4-Morpholinyl)phenyl]amino]-4-pyrimidinyl]phenyl]-2-pyrrolidinecarboxamide | 5mg | $193 | 2021-12-16 | Buy |
| Ambeed | A403201 | XL019 98+% | 2mg | $48 | 2021-12-16 | Buy |
| Ambeed | A403201 | XL019 98+% | 5mg | $62 | 2021-12-16 | Buy |
| Ambeed | A403201 | XL019 98+% | 10mg | $80 | 2021-12-16 | Buy |
| Ambeed | A403201 | XL019 98+% | 25mg | $104 | 2021-12-16 | Buy |
| Ambeed | A403201 | XL019 98+% | 50mg | $135 | 2021-12-16 | Buy |
| Ambeed | A403201 | XL019 98+% | 100mg | $176 | 2021-12-16 | Buy |
| Ambeed | A403201 | XL019 98+% | 250mg | $351 | 2021-12-16 | Buy |
| Ambeed | A403201 | XL019 98+% | 1g | $876 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024547 | XL-019 95.00% | 1MG | $340.2 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024547 | XL-019 95.00% | 5MG | $496.95 | 2021-12-16 | Buy |
| ApexBio Technology | A3937 | XL019 | 5mg | $90 | 2021-12-16 | Buy |
| ApexBio Technology | A3937 | XL019 | 50mg | $450 | 2021-12-16 | Buy |
| Axon Medchem | Axon2231 | XL019 99% | 2x5mg | $176 | 2021-12-16 | Buy |
| Axon Medchem | Axon2231 | XL019 99% | 25mg | $385 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146222 | XL019 >98% | 100mg | $838.1 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥11.125 mg/mL in DMSO
form :solid
color :Green to yellow
solubility :insoluble in EtOH; insoluble in H2O; ≥11.125 mg/mL in DMSO
form :solid
color :Green to yellow
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. Many myeloproliferative diseases have been linked to a mutation in JAK2 where a switch from valine to phenylalanine occurs at the 617 position (V617F). Furthermore, constitutive activation of the JAK2 signaling pathway is associated with aggressive adult T cell leukemia/lymphoma. XL019 is a potent, bioavailable JAK inhibitor with preference for JAK2 (IC50 = 2 nM) over JAK1 and JAK3 (IC50s = 130 and 250 nM, respectively). It is effective against JAK2V617F as well as JAK2 and inhibits phosphorylation of STAT5 in vivo.More related product prices
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