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ChemicalBook >> CAS DataBase List >> AG 18

AG 18

AG 18 price.
  • $34 - $1744
  • Product name: AG 18
  • CAS: 118409-57-7
  • MF: C10H6N2O2
  • MW: 186.17
  • EINECS:
  • MDL Number:MFCD00133899
  • Synonyms:RARECHEM AL BX 0069;RG-50810;TYRPHOSTIN RG 50858;TYRPHOSTIN AG 18;TYRPHOSTIN A23;TYRPHOSTIN 23;ALPHA-CYANO-(3,4-DIHYDROXY)CINNAMONITRILE;AG 18
33 prices
Selected condition:
Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 50
  • 10mg
  • 10
  • 25mg
  • 50mg
  • 100MG
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number2085AH
  • Product descriptionTyrphostin 23
  • Packaging1g
  • Price$527
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2085AH
  • Product descriptionTyrphostin 23
  • Packaging50mg
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60308
  • Product descriptionTyrphostin A23, 99%
  • Packaging5mg
  • Price$73.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60308
  • Product descriptionTyrphostin A23, 99%
  • Packaging10mg
  • Price$126.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60308
  • Product descriptionTyrphostin A23, 99%
  • Packaging25mg
  • Price$321
  • Updated2023-06-20
  • Buy
  • ManufacturerAmbeed
  • Product numberA423886
  • Product description2-(3,4-Dihydroxybenzylidene)malononitrile 98+%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA423886
  • Product description2-(3,4-Dihydroxybenzylidene)malononitrile 98+%
  • Packaging10mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA423886
  • Product description2-(3,4-Dihydroxybenzylidene)malononitrile 98+%
  • Packaging250mg
  • Price$513
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA423886
  • Product description2-(3,4-Dihydroxybenzylidene)malononitrile 98+%
  • Packaging1g
  • Price$1744
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000257
  • Product descriptionTYRPHOSTIN A-23 95.00%
  • Packaging5MG
  • Price$145.2
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000257
  • Product descriptionTYRPHOSTIN A-23 95.00%
  • Packaging25MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000257
  • Product descriptionTYRPHOSTIN A-23 95.00%
  • Packaging250MG
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1173
  • Product descriptionAG 18
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1173
  • Product descriptionAG 18
  • Packaging25mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010300
  • Product descriptionAG 18 >98%
  • Packaging5mg
  • Price$34
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010300
  • Product descriptionAG 18 >98%
  • Packaging10mg
  • Price$64
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2085AH Tyrphostin 23 1g $527 2021-12-16 Buy
AK Scientific 2085AH Tyrphostin 23 50mg $178 2021-12-16 Buy
Alfa Aesar J60308 Tyrphostin A23, 99% 5mg $73.65 2024-03-01 Buy
Alfa Aesar J60308 Tyrphostin A23, 99% 10mg $126.65 2024-03-01 Buy
Alfa Aesar J60308 Tyrphostin A23, 99% 25mg $321 2023-06-20 Buy
Ambeed A423886 2-(3,4-Dihydroxybenzylidene)malononitrile 98+% 5mg $50 2021-12-16 Buy
Ambeed A423886 2-(3,4-Dihydroxybenzylidene)malononitrile 98+% 10mg $79 2021-12-16 Buy
Ambeed A423886 2-(3,4-Dihydroxybenzylidene)malononitrile 98+% 250mg $513 2021-12-16 Buy
Ambeed A423886 2-(3,4-Dihydroxybenzylidene)malononitrile 98+% 1g $1744 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000257 TYRPHOSTIN A-23 95.00% 5MG $145.2 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000257 TYRPHOSTIN A-23 95.00% 25MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000257 TYRPHOSTIN A-23 95.00% 250MG $1732.5 2021-12-16 Buy
ApexBio Technology A1173 AG 18 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A1173 AG 18 25mg $104 2021-12-16 Buy
Cayman Chemical 10010300 AG 18 >98% 5mg $34 2024-03-01 Buy
Cayman Chemical 10010300 AG 18 >98% 10mg $64 2024-03-01 Buy

Properties

Melting point :225°C
Boiling point :421.1±45.0 °C(Predicted)
Density :1.428±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO, ethanol, or DMF
pka :7.26±0.18(Predicted)
form :Yellow solid
color :Yellow
λmax :464nm(DMSO)(lit.)
Stability :Store in refrigerator

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H371 May cause damage to organs Specific target organ toxicity, single exposure Category 2 Warning P260, P264, P270, P309+P311, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Tyrphostin inhibit protein tyrosine kinase and block the EGF-dependent autophosphorylation of the receptor. The inhibitors can bind to the EGF receptor kinase domain with different affinities. It also inhibits PDGFR kinase. Tyrphostin A23 has been used to inhibit agonist-induced GP IIb- IIIa activation in permeabilized platelets and in other studies to block calcium channel currents in vascular smooth muscle cells. . Tyrphostin A23 can also inhibit the internalization of (125)I-transferrin in Heb7a cells.

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