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ChemicalBook >> CAS DataBase List >> ascochlorin

ascochlorin

ascochlorin price.
  • $288 - $3150
  • Product name: ascochlorin
  • CAS: 26166-39-2
  • MF: C23H29ClO4
  • MW: 404.931
  • EINECS:
  • MDL Number:MFCD01939947
  • Synonyms:3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,4E)-3-methyl-5-[(1R)-1β,2β,6β-trimethyl-3-oxocyclohexyl]-2,4-pentadienyl]benzaldehyde;Ilicicolin D;3-Chloro-4,6-dihydroxy-2-methyl-5-(3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)-2,4-pentadienyl)benzaldehyde (1R-(1alpha(2E,4E),2beta,6beta))-;Antibiotic ll-Z1272 gamma;ascochlorin;Benzaldehyde, 3-chloro-4,6-dihydroxy-2-methyl-5-(3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)-2,4-pentadienyl)-, (1R-(1alpha(2E,4E),2beta,6beta))-;beta-Resorcylaldehyde, 5-chloro-6-methyl-3-(3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)-2,4-pentadienyl)-, (E,E)-;Ll-Z 1272 gamma
6 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 500μg
  • 500ug
  • 0.5MG
  • 1MG
  • 2.5mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0025816
  • Product descriptionASCOCHLORIN 95.00%
  • Packaging0.5MG
  • Price$549
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0025816
  • Product descriptionASCOCHLORIN 95.00%
  • Packaging1MG
  • Price$1044.75
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19437
  • Product descriptionAscochlorin ≥98%
  • Packaging500μg
  • Price$288
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19437
  • Product descriptionAscochlorin ≥98%
  • Packaging2.5mg
  • Price$1147
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberA787028
  • Product descriptionAscochlorin
  • Packaging2.5mg
  • Price$3150
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberA3690
  • Product descriptionAscochlorin
  • Packaging500ug
  • Price$523
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0025816 ASCOCHLORIN 95.00% 0.5MG $549 2021-12-16 Buy
American Custom Chemicals Corporation API0025816 ASCOCHLORIN 95.00% 1MG $1044.75 2021-12-16 Buy
Cayman Chemical 19437 Ascochlorin ≥98% 500μg $288 2024-03-01 Buy
Cayman Chemical 19437 Ascochlorin ≥98% 2.5mg $1147 2024-03-01 Buy
TRC A787028 Ascochlorin 2.5mg $3150 2021-12-16 Buy
Usbiological A3690 Ascochlorin 500ug $523 2021-12-16 Buy

Properties

Melting point :172-174 °C
Boiling point :556.9±39.0 °C(Predicted)
Density :1.199±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble
form :A powder
pka :6.26±0.50(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ascochlorin is an isoprenoid antibiotic and antiviral that has diverse effects on mammalian cells. It suppresses PMA-induced invasion in renal carcinoma cells (IC50 = ~10 μM) by inhibiting the expression of matrix metalloproteinase-9. At 2 μM, ascochlorin profoundly increases the expression of p53 by increasing protein stability in cancer cells, and, at 50 μm, it inhibits signaling through STAT3. Ascochlorin also binds and inhibits the mitochondrial cytochrome bc1 complex, blocking reduction of cytochrome b by ubiquinone.