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ChemicalBook >> CAS DataBase List >> siomycin A

siomycin A

siomycin A price.
  • $396 - $582
  • Product name: siomycin A
  • CAS: 12656-09-6
  • MF: C71H81N19O18S5
  • MW: 1648.84
  • EINECS:
  • MDL Number:
  • Synonyms:Antibiotic 6741-21;Mutabillicin;Mutabilycin;siomycin A;Mutabilycin, SporangioMycin, 6741-21, Mutabillicin;AKFVOKPQHFBYCA-OFENGFFDSA-N;Alaninamide, N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-L-valyl-2,3-didehydroalanyl-2,3-didehydroalanyl-L-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexa...;Salomycin A
Price3 Properties Safety Information Description
3 prices
Selected condition：
Brand
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 500ug
  • 500μg
  • 1000μg
  • ManufacturerCayman Chemical
  • Product number15378
  • Product descriptionSiomycin A ≥95%
  • Packaging500μg
  • Price$396
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberS497053
  • Product descriptionSiomycin A
  • Packaging1000μg
  • Price$545
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberS1013-86W
  • Product descriptionSiomycin A
  • Packaging500ug
  • Price$582
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 15378 Siomycin A ≥95% 500μg $396 2024-03-01 Buy
TRC S497053 Siomycin A 1000μg $545 2021-12-16 Buy
Usbiological S1013-86W Siomycin A 500ug $582 2021-12-16 Buy

Properties

Density :1.65±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: complete10 mg/ml, clear, colorless to faintly yellow
form :White solid.
pka :10.43±0.46(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The mammalian transcription factor forkhead box M1 (FoxM1) is induced during G1 phase, with expression continuing through S phase and mitosis. Siomycin A is a peptide thiazole antibiotic, first isolated from S. sioyaensis, that interacts with the 23S rRNA of bacteria. It inhibits FoxM1 (IC50 = ~5 μM), preventing the expression of FoxM1-regulated genes, which includes FoxM1 itself. Through this mechanism, siomycin A prevents proliferation and induces apoptosis in certain types of stem cells as well as cancer cells.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
AFINE CHEMICALS LIMITED
BOC Sciences
Hangzhou MolCore BioPharmatech Co.,Ltd.
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Aladdin Scientific Shanghai Aladdin Bio-Chem Technology Co.,LTD Shanghai EFE Biological Technology Co., Ltd. Beijing Jin Ming Biotechnology Co., Ltd. Lynnchem