奥替尼啶二盐酸盐
中文名称 | 奥替尼啶二盐酸盐 |
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中文同义词 | 奥替尼啶 奥克太啶(双盐酸盐);奥克太啶盐酸盐;奥替尼啶盐酸盐;奥替尼啶 二盐酸盐;奥替尼啶,奥克太啶;奥替尼定盐酸盐;盐酸奥替尼啶;奥替尼啶双盐酸盐 |
英文名称 | Octenidine dihydrochloride |
英文同义词 | N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis(1-octanamine) dihydrochloride;N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride;OCTENIDINE DIHYDROCHLORIDE;N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-1-octanaMine Hydrochloride;N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylaMMoniuM) dichloride;1-OctanaMine,N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, hydrochloride (1:2);ocenidine dihydrochloride;-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride |
CAS号 | 70775-75-6 |
分子式 | C36H64Cl2N4 |
分子量 | 623.82616 |
EINECS号 | 274-861-8 |
相关类别 | 抗菌;新型抗菌;医药原料药;合成;原料药;医药 抗菌剂;化妆品原料;原料药;医药原料;医用原料;医药化工原料;化工原料;化工中间体;原料;其他原料;Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;化学试剂;化工品 |
Mol文件 | 70775-75-6.mol |
结构式 |
奥替尼啶二盐酸盐 性质
熔点 | 215-217℃ |
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密度 | 1.046[at 20℃] |
蒸气压 | 0Pa at 25℃ |
储存条件 | Keep in dark place,Inert atmosphere,Room temperature |
溶解度 | 溶于二甲基亚砜和甲醇。 |
形态 | 固体 |
颜色 | 白色至类白色 |
水溶解性 | 14.2g/L at 20℃ |
Merck | 14,6754 |
稳定性 | 吸湿性 |
InChIKey | SMGTYJPMKXNQFY-UHFFFAOYSA-N |
SMILES | [N+]1(CCCCCCCCCC[N+]2C=CC(NCCCCCCCC)=CC=2)=CC=C(NCCCCCCCC)C=C1.[Cl-].[Cl-] |
LogP | 1.5 at 23℃ |
Octenidine concentrations of less than1.5 μM (0.94 μg/mL) causes a greater than 99% reduction of tested microbial population within 15 min. Staphylococcus epidermidis is the most susceptible of the test organisms, and E. coli and C. albicans are the least susceptible.
The antimicrobial activity of octenidine hydrochloride (OCT) is maintained when applied to the skin of the hands and feet of cynomolgus monkeys. Aqueous octenidine, at a concentration of 0.2 to 1.6% reduces resident microflora populations from 90 to 99.98%. A significant reduction in plaque score is observed on the buccal tooth surfaces after daily topical application of 1% solutions of octenidine and chlorhexidine for 7 d; octenidine is more effective than chlorhexidine.
安全信息
海关编码 | 2933399990 |
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更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/11/11 | XW7077575603 | 奥替尼啶二盐酸盐 | 70775-75-6 | 100G | 2601元 |
2024/11/11 | XW7077575602 | 奥替尼啶二盐酸盐 | 70775-75-6 | 25G | 783元 |