- Bredereck’s Reagent
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- $10.00 / 1kg
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2024-08-23
- CAS:5815-08-7
- Min. Order: 1kg
- Purity: >90%
- Supply Ability: 20 tons
- Bredereck's reagent
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- $11.00 / 25g
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2024-08-07
- CAS:5815-08-7
- Min. Order: 25g
- Purity: 0.90
- Supply Ability: 200kg
- polyamines
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- $1060.00 / 1T
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2024-05-11
- CAS:
- Min. Order: 1T
- Purity: 98%
- Supply Ability: 20T
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| | tert-Butoxy bis(dimethylamino)methane Basic information |
| Product Name: | tert-Butoxy bis(dimethylamino)methane | | Synonyms: | tert-Butoxy bis(dimethylamino)methane technical;BREDERECKS REAGENT;BREDERECK'S REAGENT;tert-Butoxybis(dimethylamino)methane, 85+%;Bis(dimethylamino)(tert-butoxy)methane;N,N,N',N'-Tetramethyl(tert-butoxy)methanediamine;N,N,N',N'-Tetramethyl-α-tert-butoxymethanediamine;α-(1,1-Dimethylethoxy)-N,N,N',N'-tetramethylmethanediamine | | CAS: | 5815-08-7 | | MF: | C9H22N2O | | MW: | 174.28 | | EINECS: | 227-383-9 | | Product Categories: | Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Polyamines;Elisa Kit-plant ELISA Kit | | Mol File: | 5815-08-7.mol |  |
| | tert-Butoxy bis(dimethylamino)methane Chemical Properties |
| Boiling point | 50-55 °C/15 mmHg (lit.) | | density | 0.844 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.422(lit.) | | Fp | 106 °F | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly) | | pka | 5.46±0.38(Predicted) | | form | Liquid | | color | Clear pale yellow | | Specific Gravity | 0.844 | | BRN | 1901973 | | Stability: | Hygroscopic | | InChI | InChI=1S/C9H22N2O/c1-9(2,3)12-8(10(4)5)11(6)7/h8H,1-7H3 | | InChIKey | HXRAMSFGUAOAJR-UHFFFAOYSA-N | | SMILES | C(OC(C)(C)C)(N(C)C)N(C)C | | CAS DataBase Reference | 5815-08-7(CAS DataBase Reference) |
| Hazard Codes | Xi,F | | Risk Statements | 10-36/37/38 | | Safety Statements | 26 | | RIDADR | UN 1993 3/PG 3 | | WGK Germany | 3 | | F | 10 | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29221990 |
| | tert-Butoxy bis(dimethylamino)methane Usage And Synthesis |
| Description |
Bredereck's reagent, chemically known as tert-Butoxy bis(dimethylamino)methane, is a versatile reagent. It can be used for a-methylation, a-methylenation, and a-amidation of multiple carbonyl systems or compounds with active CH groups. The advantage is the in situ generation of strongly basic alkanes (t-BuO-) and the generation of the corresponding iminium ions by thermal decomposition. After the Mannich reaction of the carbonyl substrate with the in situ generated iminium ion, the dimethylamine is eliminated from the adduct B- in the final step to give the condensation product, which can be converted into various types of compounds.
| | Chemical Properties | Clear pale yellow liquid | | Uses | Reactant for:
- Preparation of pyrroloquinazolines as photochemotherapeutic agents
- Enanatioslective formal synthesis of the Cinchona alkaloid quinine via stereoselective intermolecular radical addition
- Synthesis of camptothecin via intramolecular isomuenchnone cycloaddition reaction
- Aminomethylenation reactions
| | Uses | Mild enamination reagent; catalyst in ring-opening polymerization reactions. | | Uses | Reactant for:• ;Preparation of pyrroloquinazolines as photochemotherapeutic agents1• ;Enanatioslective formal synthesis of the Cinchona alkaloid quinine via stereoselective intermolecular radical addition2• ;Synthesis of camptothecin via intramolecular isomuenchnone cycloaddition reaction3• ;Aminomethylenation reactions4 |
| | tert-Butoxy bis(dimethylamino)methane Preparation Products And Raw materials |
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