- azido-PEG8-Acid
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- $0.00 / 1g
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2024-03-24
- CAS:1214319-92-2
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | N3-PEG8-CH2CH2COOH Basic information |
| Product Name: | N3-PEG8-CH2CH2COOH | | Synonyms: | N3-PEG8-CH2CH2COOH;Azido-PEG8-propionic acid;N3-PEG8-COOH;Azido-dPEG??-acid;Azido-dPEG(R)8-acid;Azido-PEG8-CH2CH2COOH;N3-PEG8-CH2CH2COOH/Propanoic acid, 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-;Azido-dPEG8-acid | | CAS: | 1214319-92-2 | | MF: | C19H37N3O10 | | MW: | 467.51118 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1214319-92-2.mol |  |
| | N3-PEG8-CH2CH2COOH Chemical Properties |
| storage temp. | -20°C | | solubility | Soluble in Water, DMSO, DCM, DMF | | form | solid or viscous liquid | | color | Colorless to light yellow |
| | N3-PEG8-CH2CH2COOH Usage And Synthesis |
| Description | Azido-PEG8-acid is a aqueous soluble PEG linker containing an azide (N3) and a terminal carboxylic acid (CO2H) group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | | reaction suitability | reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry | | Biological Activity | N3-PEG8-CH2CH2COOH is a non-cleavable ADC linker containing 8-unit PEG that can be used to synthesize antibody drug conjugates (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules. | | target | | Non-cleavable < span> | PEGs | |
| | N3-PEG8-CH2CH2COOH Preparation Products And Raw materials |
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