亚麻木酚素
中文名称 | 亚麻木酚素 |
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中文同义词 | (S,S)-亚麻木酚素 |
英文名称 | Secoisolariciresinol diglucoside |
英文同义词 | β-D-Glucopyranoside, (2S,3S)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediyl bis-;Secoisolariciresinoldiglucoside/(SS)-Secoisolariciresinoldiglucoside;(S,S)-SDG;(S,S)-Secoisolariciresinol diglucoside |
CAS号 | 257930-74-8 |
分子式 | C32H46O16 |
分子量 | 686.7 |
EINECS号 | |
相关类别 | 木脂素 |
Mol文件 | 257930-74-8.mol |
结构式 | ![]() |
亚麻木酚素 性质
沸点 | 989.2±65.0 °C(Predicted) |
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密度 | 1.52±0.1 g/cm3(Predicted) |
酸度系数(pKa) | 9.80±0.20(Predicted) |
形态 | 固体 |
颜色 | 白色至米白色 |
Secoisolariciresinol diglucoside (1-500 μM) possesses strong reducing power and high free radical scavenging activity for hydroxyl, peroxyl and DPPH free radicals.
Secoisolariciresinol diglucoside (1-50 μM; 24 h) attenuates human monocyte adhesion to and migration across human brain endothelial monolayers.
Secoisolariciresinol diglucoside (4 mg/mouse; a single p.o.) diminishes leukocyte adhesion and migration across blood-brain barrier (BBB) in neuroinflammation.
Animal Model: | Hand feeding mice (10 weeks old, male) are injected with TNFα |
Dosage: | 4 mg/mouse |
Administration: | P.o. 2 h before i.c. administration of TNFα |
Result: | Attenuated adhesion of leukocytes to the endothelium by 50% and attenuated migration of leukocytes across the BBB by 64%. |