| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Piperilate
CAS:4546-39-8
Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
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Pipethanate manufacturers
- Piperilate
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- $1980.00 / 50mg
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2024-10-28
- CAS:4546-39-8
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Pipethanate Basic information |
| Product Name: | Pipethanate | | Synonyms: | Pipethanate;Benzilic acid 2-piperidinoethyl ester;Hydroxydiphenylacetic acid 2-piperidinoethyl ester;α-Hydroxy-α,α-diphenylacetic acid 2-(1-piperidyl)ethyl ester;Benzeneacetic acid, α-hydroxy-α-phenyl-, 2-(1-piperidinyl)ethyl ester | | CAS: | 4546-39-8 | | MF: | C21H25NO3 | | MW: | 339.43 | | EINECS: | | | Product Categories: | | | Mol File: | 4546-39-8.mol |  |
| | Pipethanate Chemical Properties |
| Melting point | 168-169 °C | | Boiling point | 444.1±24.0 °C(Predicted) | | density | 1.155±0.06 g/cm3(Predicted) | | pka | 11.34±0.29(Predicted) |
| | Pipethanate Usage And Synthesis |
| Originator | Panpurol ,Nippon Shinyaku, Japan | | Definition | ChEBI: Pipethanate is a diarylmethane. | | Manufacturing Process | Pipethanate hydrochloride is dissolved in water and the solution is made alkaline by adding 10% sodium hydroxide solution. The crystals that are separated are filtered off and recrystallized from dilute ethanol. The monohydrate thereby obtained is dehydrated at 100°C under reduced pressure for 20 minutes. The products that are now in the form of a syrup due to loss of water of crystallization are further dehydrated for 2 days in a desiccator over phosphorus pentoxide whereupon the anhydrous pipethanate is obtained.
3.8 g of the anhydrous pipethanate prepared by the method described is dissolved in 15 cc of acetone, 18 g of purified ethyl bromide is added, and the mixture heated for 8 hours in a sealed tube at 100°C to 110°C. After cooling the crystals are separated and isolated by filtration. They are then washed with acetone to give 5.2 g (95.6%) of pipethanate ethylbromide with a decomposition point of 218°C to 220°C. The crystals are almost pure. | | Therapeutic Function | Anticholinergic, Antiulcer |
| | Pipethanate Preparation Products And Raw materials |
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