Company Name: |
TargetMol Chemicals Inc.
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4008200310 |
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marketing@tsbiochem.com |
Products Intro: |
Product Name:Piperilate CAS:4546-39-8 Purity:98% Package:100 mg;5 mg;50 mg
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| Pipethanate Basic information |
Product Name: | Pipethanate | Synonyms: | Pipethanate;Benzilic acid 2-piperidinoethyl ester;Hydroxydiphenylacetic acid 2-piperidinoethyl ester;α-Hydroxy-α,α-diphenylacetic acid 2-(1-piperidyl)ethyl ester;Benzeneacetic acid, α-hydroxy-α-phenyl-, 2-(1-piperidinyl)ethyl ester | CAS: | 4546-39-8 | MF: | C21H25NO3 | MW: | 339.43 | EINECS: | | Product Categories: | | Mol File: | 4546-39-8.mol | ![Pipethanate Structure](CAS/GIF/4546-39-8.gif) |
| Pipethanate Chemical Properties |
Melting point | 168-169 °C | Boiling point | 444.1±24.0 °C(Predicted) | density | 1.155±0.06 g/cm3(Predicted) | pka | 11.34±0.29(Predicted) |
| Pipethanate Usage And Synthesis |
Originator | Panpurol ,Nippon Shinyaku, Japan | Definition | ChEBI: Pipethanate is a diarylmethane. | Manufacturing Process | Pipethanate hydrochloride is dissolved in water and the solution is made alkaline by adding 10% sodium hydroxide solution. The crystals that are separated are filtered off and recrystallized from dilute ethanol. The monohydrate thereby obtained is dehydrated at 100°C under reduced pressure for 20 minutes. The products that are now in the form of a syrup due to loss of water of crystallization are further dehydrated for 2 days in a desiccator over phosphorus pentoxide whereupon the anhydrous pipethanate is obtained. 3.8 g of the anhydrous pipethanate prepared by the method described is dissolved in 15 cc of acetone, 18 g of purified ethyl bromide is added, and the mixture heated for 8 hours in a sealed tube at 100°C to 110°C. After cooling the crystals are separated and isolated by filtration. They are then washed with acetone to give 5.2 g (95.6%) of pipethanate ethylbromide with a decomposition point of 218°C to 220°C. The crystals are almost pure. | Therapeutic Function | Anticholinergic, Antiulcer |
| Pipethanate Preparation Products And Raw materials |
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