- (S)-DTBM-Segphos
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- $0.00 / 1g
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2023-10-19
- CAS:210169-40-7
- Min. Order: 1g
- Purity: 98%, ee＞99
- Supply Ability: 2kg
- (S)-DTBM-SEGPHOS
-
- $0.00 / 1KG
-
2022-12-22
- CAS:210169-40-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20 mt
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| | (S)-(+)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(S)-DTBM-SEGPHOS Basic information | | Reaction |
| Product Name: | (S)-(+)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(S)-DTBM-SEGPHOS | | Synonyms: | (S)-(+)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(S)-DTBM-SEGPHOS;(S)-(+)-5,5μ-Bis[di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-4,4μ-bi-1,3-benzodioxole;(S)-DTBM-SEGPHOS(R);(S)-DTBM-SEGPHOS;(S)-5,5'-Bis[bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-4,4'-bibenzodioxole;(S)-DTBM-SEGPHOS(R) >=94%;Phosphine,[(4S)-[4,4'-bi-1,3-benzodioxole]-5,5'-diyl]bis[bis[3,5-bis(1,1-diMethylethyl)-4-Methoxyphenyl]-;(S)-(+)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole, min. 98% | | CAS: | 210169-40-7 | | MF: | C74H100O8P2 | | MW: | 1179.53 | | EINECS: | | | Product Categories: | Chiral Phosphine;Segphos Series | | Mol File: | 210169-40-7.mol | ![(S)-(+)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(S)-DTBM-SEGPHOS Structure](CAS/GIF/210169-40-7.gif) |
| | (S)-(+)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(S)-DTBM-SEGPHOS Chemical Properties |
| Melting point | 126-128°C | | Boiling point | 987.3±65.0 °C(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | Powder | | color | off-white | | CAS DataBase Reference | 210169-40-7 |
| WGK Germany | 3 | | HS Code | 2932.99.7000 |
| | (S)-(+)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(S)-DTBM-SEGPHOS Usage And Synthesis |
| Reaction |
- Biaryl bisphosphine ligand with narrow dihedral angle. The DTBM SEGPHOS® ligand, as the ruthenium complex, gives superior enantioselectivity and diastereoselectivity through dynamic kinetic resolution in the asymmetric hydrogenation of a-substituted-β-ketoesters useful in the synthesis of carbapenum antibiotics.
- With rhodium, preferential enantioselective hydrogenation of more reactive olefin of extended enone structure.
- Rhodium catalyzed chemo-, regio, and entantioselective [2 + 2 + 2] cycloaddition of alkynes with isocyanates.
- With copper, enantioselective cross Aldol-type reaction of acetonitrile.
- With copper, enantioselective vinylsilane alkenylation of aldehydes.
- Gold carbene mediated stereoselective cyclopropanation of propargyl esters.
- With copper, enantioselective 1,2-reduction of ketones, and 1,4-reduction of a α,β-usaturated esters.
- With copper, catalytic enantioselective Mannich-type reaction.
- Enantioselective fluorination of b β-keto esters, tert-butoxycarbonyl lactones and lactmes with Sodeoka's Pd-aqua complex and a fluorinating reagent.
- Rh-catalyzed intramolecular olefin or carbonyl hydroacylation.
| | Uses | Catalytic ligand for:
- Enantioselective synthesis of secondary allylic alcohols via enantioselective reductions of α,β-unsaturated ketones
- Stereoselective preparation of cyclohexanone derivatives via rhodium-catalyzed rearrangement of allyl or allenic cyclobutanols
- Cu-catalyzed asymmetric conjugate reduction of beta-substituted unsaturated phosphonates to give optically active beta-stereogenic alkylphosphonates
- Asymmetric synthesis of cyclohexenones via Rh-catalyzed desymmetrization through enantioselective C-C bond activation and ring expansion of allenyl cyclobutanols
- Enantioselective synthesis and crystal structure of P-stereogenic alkynylphosphine oxides by Rh-catalyzed [2+2+2] cycloaddition
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| | (S)-(+)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(S)-DTBM-SEGPHOS Preparation Products And Raw materials |
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