MPEG5-NHS

MPEG5-NHS Suppliers list
Company Name: 9i LLC
Tel: +18039569191
Email: MWan@NiNeiLab.com
Products Intro: Product Name:mPEG5-CH2CH2COONHS Ester
CAS:1449390-12-8
Purity:min.97% Package:296USD/1 g Remarks:NA209
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Products Intro: Product Name:MPEG5-NHS
CAS:1449390-12-8
Package:1kg,2kg,5kg,10kg,25kg
Company Name: SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel: +86-021-61551413 +8618813727289
Email: contact@trustwe.com
Products Intro: Product Name:mPEG5-NHS Ester
CAS:1449390-12-8
Purity:98% Package:Package as requetsed
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:m-PEG6-NHS ester
CAS:1449390-12-8
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Wuhan Borenpharm Co., Ltd
Tel: 027-65563561 18717150066
Email: 3207347307@qq.com
Products Intro: Product Name:Methyl-PEG5-NHS ester
CAS:1449390-12-8
Purity:0.95 Package:1g;283.87USD|5g;582.67USD

MPEG5-NHS manufacturers

  • m-PEG6-NHS ester
  • m-PEG6-NHS ester pictures
  • $0.00 / 1g
  • 2024-03-27
  • CAS:1449390-12-8
  • Min. Order: 1g
  • Purity: >98.00%
  • Supply Ability: 1g
MPEG5-NHS Basic information
Product Name:MPEG5-NHS
Synonyms:MPEG5-NHS;m-PEG6-NHS ester;mPEG5-CH2CH2COONHS Ester;mPEG6-NHS;4,7,10,13,16,19-Hexaoxaeicosanoic acid, 2,5-dioxo-1-pyrrolidinyl ester;Methyl-PEG5-NHS ester;mPEG5-SPA;mPEG5-CH2CH2COONHS/4,7,10,13,16,19-Hexaoxaeicosanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
CAS:1449390-12-8
MF:C18H31NO10
MW:421.44
EINECS:
Product Categories:mPEG
Mol File:1449390-12-8.mol
MPEG5-NHS Structure
MPEG5-NHS Chemical Properties
Boiling point 502.6±60.0 °C(Predicted)
density 1.21±0.1 g/cm3(Predicted)
solubility Soluble in DMSO, DCM, DMF
form Liquid
color Colorless to light yellow
Safety Information
MSDS Information
MPEG5-NHS Usage And Synthesis
Descriptionm-PEG6-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological ActivityMPEG5-NHS is a non-cleavable 6-unit PEG-containing ADC linker for the synthesis of antibody drug conjugates (ADCs). It is a PROTAC linker belonging to the PEG/Alkyl/ether class, which can be used to synthesize PROTAC molecules.
in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

PEGs

Alkyl/ether

Non-cleavable

MPEG5-NHS Preparation Products And Raw materials
Tag:MPEG5-NHS(1449390-12-8) Related Product Information
m-PEG8-NHS ester MPEG4-NHS MPEG3-NHS MPEG11-NHS MPEG36-OH MPEG24-OH MPEG48-OH Pentaethylene glycol mono methyl ether tosylate MPEG8-NH-Mal MPEG6-Mal 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanoic acid Mal-PEG3-alcohol 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol 2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoate MAl-PEG6-t-butyl ester Mal-PEG4-NHS ester alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol) MPEG12-Mal