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| 1-Bromo-4-chloro-2-fluorobenzene Basic information |
| 1-Bromo-4-chloro-2-fluorobenzene Chemical Properties |
Boiling point | 91-92 °C/20 mmHg (lit.) | density | 1.678 g/mL at 25 °C (lit.) | refractive index | n20/D 1.556(lit.) | Fp | 198 °F | storage temp. | Sealed in dry,Room Temperature | form | Liquid | color | Clear colorless to pale yellow | Specific Gravity | 1.678 | Water Solubility | INSOLUBLE | BRN | 2081083 | InChIKey | FPNVMCMDWZNTEU-UHFFFAOYSA-N | CAS DataBase Reference | 1996-29-8(CAS DataBase Reference) |
Hazard Codes | Xi | Risk Statements | 36/37/38 | Safety Statements | 37/39-26-24/25 | WGK Germany | 3 | HazardClass | IRRITANT | HS Code | 29039990 |
| 1-Bromo-4-chloro-2-fluorobenzene Usage And Synthesis |
Chemical Properties | CLEAR COLORLESS TO PALE YELLOW LIQUID | Uses | 1-Bromo-4-chloro-2-fluorobenzene may be used in the preparation of benzonorbornadiene derivative. It may also be used as a starting material in the multi-step synthesis of AZD3264, an IKK2 (inhibitor of nuclear factor κ-B kinase-2) inhibitor. | Uses | A 2,4-dihalofluorobenzene derivative with antibacterial and antifungal activities. | General Description | 1-Bromo-4-chloro-2-fluorobenzene is a polyhalo substituted benzene. It undergoes Suzuki coupling with 2-cyanoarylboronic esters to form the corresponding biphenyls. These biphenyls are the precursors for synthesizing 6-substituted phenanthridines. The enthalpy of vaporization at boiling point (467.15K) of 1-bromo-4-chloro-2-fluorobenzene is 40.737kjoule/mol. |
| 1-Bromo-4-chloro-2-fluorobenzene Preparation Products And Raw materials |
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