ZK-90055 HYDROCHLORIDE
| 中文名称 | ZK-90055 HYDROCHLORIDE |
|---|---|
| 中文同义词 | 化合物 T13403;化合物ZK-90055盐酸盐 |
| 英文名称 | ZK-90055 (hydrochloride) |
| 英文同义词 | ZK-90055 (hydrochloride);ZK 90055 hydrochloride,ZK90055 hydrochloride |
| CAS号 | 84638-81-3 |
| 分子式 | C16H23ClN2O4 |
| 分子量 | 342.82 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 84638-81-3.mol |
| 结构式 |  |
ZK-90055 HYDROCHLORIDE 性质
| 熔点 | 187-190 °C (decomp) |
|---|---|
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
ZK-90055 hydrochloride是β2肾上腺素能受体 (β2 adrenergic receptor) 激动剂。
β2 adrenergic receptor
Contrasting a pro-drug, a soft-drug is active per se when given locally but is rapidly inactivated when it reaches the general circulation. Thus, a long duration of action at a minimum of systemic side effects may be achieved after inhalation of a h2-agonist designed in this way. One such example is ZK-90055, an indol derivative with a hydrolysable ester bond on the ring system. The development of ZK-90055 is stopped before clinical trials are commenced.