2-AMINO-2-NORBORNANECARBOXYLIC ACID manufacturers
- LAT1-IN-1
-
- $36.00 / 25mg
-
2024-11-19
- CAS:20448-79-7
- Min. Order:
- Purity: ≥98%
- Supply Ability: 10g
- LAT1-IN-1
-
- $36.00 / 25mg
-
2024-11-19
- CAS:20448-79-7
- Min. Order:
- Purity: ≥98%
- Supply Ability: 10g
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| 2-AMINO-2-NORBORNANECARBOXYLIC ACID Basic information |
Product Name: | 2-AMINO-2-NORBORNANECARBOXYLIC ACID | Synonyms: | 2-AMINO-2-NORBORNANECARBOXYLIC ACID;2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID;BCH;2-AMINO-2-NORBORNANECARBOXYLIC ACID, 98% , MIXTURE OF ISOMERS;2-Amino-2-carboxy-bicyclo-2,2,1-heptane;2-Aminonorbornane-2-carboxylic acid;B-Bch;Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-amino- | CAS: | 20448-79-7 | MF: | C8H13NO2 | MW: | 155.19 | EINECS: | | Product Categories: | | Mol File: | 20448-79-7.mol | |
| 2-AMINO-2-NORBORNANECARBOXYLIC ACID Chemical Properties |
Melting point | >300 °C(lit.) | Boiling point | 295.5±23.0 °C(Predicted) | density | 1.256±0.06 g/cm3(Predicted) | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | solubility | Aqueous Acid (Slightly) | form | Solid | pka | 2.58±0.20(Predicted) | color | White | Water Solubility | Soluble to 100 mM in water | CAS DataBase Reference | 20448-79-7(CAS DataBase Reference) |
| 2-AMINO-2-NORBORNANECARBOXYLIC ACID Usage And Synthesis |
Uses | 2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells | Definition | ChEBI: 2-Amino-2-norbornanecarboxylic acid is a monoterpenoid. | General Description | 2-Amino-2-norbornanecarboxylic acid is a potential large amino acid transporters inhibitor. It may suppress tumor progression and apoptosis. | Biochem/physiol Actions | 2-Amino-2-norbornanecarboxylic acid (BCH) is a Na(+)-independent system L specific substrate used with other system specific substrates such as the system A specific substrate α-(methylamino) isobutyric acid and system N specific substrate L-glutamic acid gamma-monohydroxamate to help identify, differentiate and characterize amino acid transport systems in cells. | storage | Store at RT |
| 2-AMINO-2-NORBORNANECARBOXYLIC ACID Preparation Products And Raw materials |
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