| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:TIQ-A
CAS:420849-22-5
Package:50Mg,5Mg
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| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:TIQ-A
CAS:420849-22-5
Purity:98% Package:1G;10G;100G
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| Product Name: | TIQ-A | | Synonyms: | Thieno[2,3-c]isoquinolin-5(4H)-one;TIQ-A,poly ADP ribose polymerase,ADP-ribosyltransferase,TIQA,Inhibitor,PARP,TIQ A,inhibit,tankyrases,ADP-ribosylation,poly-ART | | CAS: | 420849-22-5 | | MF: | C11H7NOS | | MW: | 201.24 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 420849-22-5.mol |  |
| | TIQ-A Chemical Properties |
| Melting point | 256-258°C | | Boiling point | 282.2±9.0 °C(Predicted) | | density | 1.358±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: 16 mg/mL, soluble | | pka | 13.04±0.20(Predicted) | | form | solid | | color | Light green to green |
| Hazard Codes | Xn | | Risk Statements | 20/21/22 | | WGK Germany | 3 |
| | TIQ-A Usage And Synthesis |
| Chemical Properties | Dark Brown Solid | | Uses | A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and in vivi in rat transient focal ischemia model (3 mg/kg ip). |
| | TIQ-A Preparation Products And Raw materials |
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