DPQ

DPQ Suppliers list
Company Name: TargetMol Chemicals Inc.
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Email: support@targetmol.com
Products Intro: Product Name:DPQ
CAS:129075-73-6
Package:50mg;1230USD|100mg;1870USD|25mg;947USD
Company Name: SUZHOU SENFEIDA CHEMICAL CO.,LTD
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Products Intro: Product Name:DPQ
CAS:129075-73-6
Purity:99.9% Package:200kg
Company Name: Aladdin Scientific
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Products Intro: Product Name:DPQ
CAS:129075-73-6
Purity:>=99% Package:$107.9/1mg;$325.9/5mg;Bulk package Remarks:99%
Company Name: J & K SCIENTIFIC LTD.  
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Products Intro: Product Name:3,4-Dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone
CAS:129075-73-6
Package:2.5Mg,25Mg,5Mg
Company Name: SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD  
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Products Intro: Product Name:DPQ
CAS:129075-73-6
Purity:98% Package:10mg,100mg,500mg,1g,10g

DPQ manufacturers

  • DPQ
  • DPQ pictures
  • $1230.00 / 50mg
  • 2024-10-24
  • CAS:129075-73-6
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  • Supply Ability: 10g
DPQ Basic information
Product Name:DPQ
Synonyms:PARP Inhibitor III, DPQ;DPQ;3,4-DIHYDRO-5-[4-(1-PIPERIDINYL)BUTOXY]-1(2H)-ISOQUINOLINONE;3,4-DIHYDRO-5[4-(1-PIPERIDINYL)BUTOXYL]-1(2H)-ISOQUINOLINE;3,4-DIHYDRO-5-[4-(1-PIPERIDINYL)BUTOXYL]-1(2H)-ISOQUINOLINONE;3,4-DIHYDRO-5[4-(1-PIPERINDINYL)BUTOXY]-1(2H)-ISOQUINOLINE;5-[4-(1-PIPERIDINYL)-BUTYLOXY]-1,2,3,4-TETRAHYDROISOQUINOLIN-1-ONE;DMEM(Low Glucose)
CAS:129075-73-6
MF:C18H26N2O2
MW:302.41
EINECS:
Product Categories:
Mol File:129075-73-6.mol
DPQ Structure
DPQ Chemical Properties
Melting point 107-109°
Boiling point 528.8±50.0 °C(Predicted)
density 1.096±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: Soluble
form solid
pka14.54±0.20(Predicted)
color White to off-white
biological sourcesynthetic (organic)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
DPQ Usage And Synthesis
DescriptionThe poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. DPQ is a potent inhibitor of PARPs, inhibiting PARP1 with an IC50 value of 40 nM. It is approximately 10-fold less potent against PARP2. DPQ can be used in either cells or in animals.
UsesDPQ has been used as a PARP1 (poly(ADP-ribose) polymerase 1) inhibitor in in vivo studies to determine the loss of γ-H2AX (H2A histone family member X) upon irradiation.
UsesReagent for inhibition of PARP.
Uses3,4-Dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone is a potent inhibitor of poly(ADP-ribose) polymerases, a family of enzymes that plays a crucial role in DNA repair and apoptosis in respons e to reactive oxygen and nitrogen species.
Biochem/physiol Actions3,4-Dihydro-5-[4-(1-piperidinyl)butoxyl]-1(2H)-isoquinolinone (DPQ) is known to decrease the PARP 1 (poly(ADP-ribose) polymerase 1) mediated apoptosis under the influence of ischemia. It is considered as more effective inhibitor than the traditionally used PARP1 inhibitor 3-aminobenzamide.
storage+4°C
DPQ Preparation Products And Raw materials
Tag:DPQ(129075-73-6) Related Product Information
4-AMINO-1,8-NAPHTHALIMIDE 3-Aminobenzamide NU1025 DMEM/F12 medium DMEM medium 4-Hydroxyquinazoline Rucaparib ABT-888 1,5-ISOQUINOLINEDIOL 1(2H)-Isoquinolinone, 5-aMino-, Monohydrochloride 5-Benzoyloxy-1(2H)-isoquinolinone 3-(4-CHLORO-PHENYL)-QUINOXALINE-5-CARBOXYLIC ACID AMIDE TIQ-A 5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE DPQ 5-HYDROXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-5-OL DULBECCO'S MODIFIED EAGLE'S MEDIUM W/L-&

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