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5-Bromo-2-nitropyridine

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Company Name: Changzhou Fullone Chemical Co., Ltd.
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Products Intro: Product Name:5-Bromo-2-nitropyridine
CAS:39856-50-3
Purity:98% Package:1kg; 5kg; 25kg
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Products Intro: Product Name:5-Bromo-2-nitropyridine
CAS:39856-50-3
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CAS:39856-50-3
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Products Intro: Product Name:5-Bromo-2-nitropyridine
CAS:39856-50-3
Purity:99.9% Package:1kg;100USD
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Products Intro: Product Name:5-Bromo-2-nitropyridine
CAS:39856-50-3
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5-Bromo-2-nitropyridine manufacturers

  • 5-Bromo-2-nitropyridine
  • 5-Bromo-2-nitropyridine pictures
  • $0.00 / 1KG
  • 2024-09-06
  • CAS:39856-50-3
  • Min. Order: 1KG
  • Purity: 98%min
  • Supply Ability: 30tons/month
5-Bromo-2-nitropyridine Basic information
Product Name:5-Bromo-2-nitropyridine
Synonyms:AKOS BBS-00001330;5-BROMO-2-NITROPYRIDINE;3-BROMO-6-NITROPYRIDINE;2-NITRO-5-BROMO PYRIDINE(5-BROMO-2-NITROPYRIDINE);5-BROMO-2-NITROPYRIDINE, 98+%;3-Bromo-6-nitropyridine (5-Bromo-2-nitropyridine);5-Bromo-2-notropyridine;5-Bromo-2-nitropyrid
CAS:39856-50-3
MF:C5H3BrN2O2
MW:202.99
EINECS:609-748-8
Product Categories:Heterocycle-Pyridine series;blocks;Bromides;Pyridines;Pyridine;Pyridines, Pyrimidines, Purines and Pteredines;Organohalides;Bromopyridines;Halopyridines;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyridines derivates;39856-50-3
Mol File:39856-50-3.mol
5-Bromo-2-nitropyridine Structure
5-Bromo-2-nitropyridine Chemical Properties
Melting point 148-150 °C (lit.)
Boiling point 292.3±20.0 °C(Predicted)
density 1.833±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka-4.95±0.22(Predicted)
color White to yellow to beige powder or crystal or chunks
BRN 120878
InChIInChI=1S/C5H3BrN2O2/c6-4-1-2-5(7-3-4)8(9)10/h1-3H
InChIKeyATXXLNCPVSUCNK-UHFFFAOYSA-N
SMILESC1([N+]([O-])=O)=NC=C(Br)C=C1
CAS DataBase Reference39856-50-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37
WGK Germany 3
HazardClass IRRITANT
PackingGroup III
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
5-Bromo-2-nitropyridine Usage And Synthesis
Chemical PropertiesColorless solid
Uses5-Bromo-2-nitropyridine is employed as a reagent in the synthesis of novel benzinidazoles, potent inhibitors of TIE-2 and VEGFR-2 Tyrosine (T899975) kinase receptors.
Preparation5-Bromo-2-nitropyridine was prepared from the corresponding amine via hydrogen peroxide oxidation in large scale production. N-Bromosuccinimide (NBS) bromination of 2-aminopyridine in acetonitrile at 0-5 °C delivered 5-bromo-2- aminopyridine with good regioselectivity (>20:1). The brominated amino-pyridine was then reacted with the oxidant mixture, yielding 5-Bromo-2-nitropyridine after dilution with water and isopropanol[1].
5-Bromo-2-nitropyridine
Synthesis Reference(s)[1] Agosti, Alessandro, et al. "Handling Hydrogen Peroxide Oxidations on a Large Scale: Synthesis of 5-Bromo-2-nitropyridine." Organic Process Research & Development 21.3(2017):451-459.
Tag:5-Bromo-2-nitropyridine(39856-50-3) Related Product Information
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