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| | 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Basic information |
| Product Name: | 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt | | Synonyms: | 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt;4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt;4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate Sodium Salt;4-Methyl-7-[(6-O-sulfo-β-D-galactopyranosyl)oxy]-;4-Methyl-7-[(6-O-sulfo-beta-D-galactopyranosyl)oxy]-2H-1-benzopyran-2-one monosodium salt;[(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl sulfate;[(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methoxysulfonyloxysodium;4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt | | CAS: | 206443-06-3 | | MF: | C16H17NaO11S | | MW: | 440.35435 | | EINECS: | 1533716-785-6 | | Product Categories: | Carbohydrates & Derivatives;Fluorescent Labels & Indicators | | Mol File: | 206443-06-3.mol |  |
| | 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Chemical Properties |
| Melting point | 196-198?C | | storage temp. | -20°C Freezer, Under Inert Atmosphere | | solubility | Methanol (Slightly, Sonicated), Water (Slightly) | | form | Solid | | color | White to Off-White | | Stability: | -20?C Freezer, Under Inert Atmosphere |
| | 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Usage And Synthesis |
| Description | 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency. | | Chemical Properties | White Solid | | Uses | Used for the determination of galactose-6-sulphate sulphatase activity. Used in the diagnosis of Mucopolysaccharidosis IV A. | | Uses | 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt is used for the determination of galactose-6-sulphate sulphatase activity,it is used in the diagnosis of Mucopolysaccharidosis IV A. |
| | 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt Preparation Products And Raw materials |
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