| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Vadocaine
CAS:72005-58-4
Purity:详情请见官网 Package:100 mg;5 mg;25 mg;10 mg;50 mg;1 mg
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| | vadocaine Basic information |
| Product Name: | vadocaine | | Synonyms: | vadocaine;N-(2-Methoxy-4,6-dimethylphenyl)-2-methyl-1-piperidinepropanamide;OR-K-242;Vadocaina;Vadocainum | | CAS: | 72005-58-4 | | MF: | C18H28N2O2 | | MW: | 304.431 | | EINECS: | | | Product Categories: | | | Mol File: | 72005-58-4.mol |  |
| | vadocaine Chemical Properties |
| | vadocaine Usage And Synthesis |
| Originator | Vadocaine hydrochloride ,ZYF Pharm Chemical | | Manufacturing Process | 3-Chloro-4',6'-dimethyl-o-propananisidide was prepared by using 92.8 g
(0.615 mol) 4,6-dimethyl-o-anisidine and 86 g (0.68 mol) of 3-chloropropionyl
chloride, melting point 123-125°C. A mixture containing 40 g (0.165 mol) of
3-chloro-4',6'-dimethyl-o-propananisidide, 54.3 g of 3-methyl piperidine, and
330 ml of anhydrous benzene was heated for 72 hours at 65°C. 47.7 g (84.5%) of N-(2-methoxy-4,6-dimethylphenyl)-2-methyl-1-
piperidinepropanamide hydrochloride was obtained by deposition of product in
anhydrous acetone saturated with hydrogen chloride; melting point 192-193°C
(crystallization from a mixture isopropanol-acetone). | | Therapeutic Function | Antitussive, Local anesthetic |
| | vadocaine Preparation Products And Raw materials |
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