(GLY14)-HUMANIN (HUMAN)

(GLY14)-HUMANIN (HUMAN) Suppliers list
Company Name: Cellmano Biotech Limited
Tel: 0551-65326643 18156095617
Email: info@cellmano.com
Products Intro: Product Name:(Gly14)-Humanin (human)
CAS:330936-70-4
Company Name: Adachibio Inc.
Tel: +8108027837258
Email: sales@adachi-bio.com
Products Intro: Product Name:(Gly14)-Humanin (human)
CAS:330936-70-4
Purity:>99% HPLC Package:5mg; 25mg; 100mg; 1g; 5g; 25g;100g
Company Name: Shenzhen Nexconn Pharmatechs Ltd
Tel: +86-755-89396905 +86-15013857715
Email: admin@nexconn.com
Products Intro: Product Name:sHNG, [Gly14]-HN, [Gly14]-Humanin
CAS:330936-70-4
Purity:98% Package:1KG;10KG;50KG
Company Name: BOC Sciences
Tel: +1-631-485-4226
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Products Intro: Product Name:(Gly14)-Humanin (human)
CAS:330936-70-4
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Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695
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Products Intro: Product Name:(GLY14)-HUMANIN (HUMAN)
CAS:330936-70-4
Purity:99% Package:1KG;7USD

(GLY14)-HUMANIN (HUMAN) manufacturers

(GLY14)-HUMANIN (HUMAN) Basic information
Product Name:(GLY14)-HUMANIN (HUMAN)
Synonyms:MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA;MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA TRIFLUOROACETATE;H-MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA-OH;[GLY14]-HN;[GLY14]-HUMANIN;[GLY14] HUMANIN G (HNG), HUMAN;(GLY14)-HUMANIN (HUMAN);[GLY14]-HUMANIN TRIFLUOROACETATE
CAS:330936-70-4
MF:C118H202N34O31S2
MW:2657.21
EINECS:
Product Categories:Alzheimers and Neurodegenerative Disease Research;Neurobiology;Neurodegenerative Disease Peptides;Other Alzheimer Peptides;OtherNeuropeptides;peptide
Mol File:330936-70-4.mol
(GLY14)-HUMANIN (HUMAN) Structure
(GLY14)-HUMANIN (HUMAN) Chemical Properties
storage temp. −70°C
form solid
color White to off-white
biological sourcehuman
Water Solubility water: 1.00-1.04mg/mL, clear, colorless
InChIKeyWUYRHUFIUFJVQU-LIRFXKSTNA-N
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
(GLY14)-HUMANIN (HUMAN) Usage And Synthesis
Uses[Gly14]-Humanin G human has been used:
  • along with bortezomib in pharmacological inhibition studies to tre at mice to limit the toxic effects of bortezomib
  • to study its effect on high glucose (HG)-induced apoptosis of endothelial cells (ECs)
  • to study its neuroprotective effects in an in vitro oxygen-glucose deprivation/reoxygenation (OGD/R) model using SH-SY5Y neuroblastoma cells
', '[Gly1?]-Humanin G human has been used to limit the toxicity during the bortezomib treatment in neonatal brachial plexus injury (NBPI) mice model. It has also been used in the cell culture of the human-derived neuroblastoma cell line.
Biological ActivityEndogenous rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimerμs disease genes and Aβ', '[Gly14]-humanin (HNG) stimulates cell growth, proliferation, and cell cycle progression. It enhances proteins such as kinases, transporters, transmembrane receptors, and transcription and translational regulators. HNG exhibits intense in vitro neuroprotective effects compared to natural HN. Studies show th at it is an effective cytoprotectant both in vitro and in vivo. HNG is found to prevent high glucose (HG)-induced apoptosis of endothelial cells (ECs). It is proven to inhibit AngII-induced phenotypic switch in vascular smooth muscle cells (VSMCs).
(GLY14)-HUMANIN (HUMAN) Preparation Products And Raw materials
Tag:(GLY14)-HUMANIN (HUMAN)(330936-70-4) Related Product Information
BIOTIN-LC-EPQ-PY-EEIPIYL AC-ASP-TYR(PO3H2)-VAL-PRO-MET-LEU-NH2 BIOTIN-LC-PTYR-GLU-GLU-ILE-OH EPQ-PY-EEIPIYL* AC-PTYR-PTYR-PTYR-ILE-GLU-OH GLY-PHE-SER L-Leu-Leu-Leu [125I]-HUMANIN (HUMAN) HUMANIN TRIFLUOROACETATE (GLY14)-HUMANIN (HUMAN)

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