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| Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate Basic information |
Product Name: | Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate | Synonyms: | 3-Pyridinepropanoic acid, 2,6-dichloro-5-fluoro-b-oxo-, ethyl ester;Ethyl 2,6-dichloro-5-fluoro-b-oxo-3-pyridinepropanoate;Ethyl 3-[2,6-dichloro-5-fluoro-(3-pyridiyl)]-3-oxopropanoate ,98%;Ethyl 3-(2,6-Dichloro-5-fluoro-3-pyridyl)-3-oxopropionate;Ethyl 3-[2,6-dichloro-5-fluoro-(3-pyridiyl)]-3-oxopropanoate,97%;ethyl 2-(2,6-dichloro-5-fluoropyridin-3-yl)-3-oxobutanoate;2,6-Dichloro-5-Fluoronicothinic acetale;Ethyl 2,6-dichloro-5-fluornicotinoylacetate ,98% | CAS: | 96568-04-6 | MF: | C10H8Cl2FNO3 | MW: | 280.08 | EINECS: | 627-012-4 | Product Categories: | Pharmaceutical Intermediates;Intermediate of Enoxacin;Pyridines;Heterocyclic Building Blocks;Halogenated Heterocycles;C9 to C46Heterocyclic Building Blocks;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | Mol File: | 96568-04-6.mol | ![Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate Structure](CAS/GIF/96568-04-6.gif) |
| Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate Chemical Properties |
Melting point | 68-72 °C (lit.) | Boiling point | 349.9±37.0 °C(Predicted) | density | 1.4602 (estimate) | storage temp. | Sealed in dry,Store in freezer, under -20°C | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | form | Solid | pka | 9.43±0.50(Predicted) | color | White to Off-White | InChIKey | IEUHWNLWVMLHHC-UHFFFAOYSA-N | CAS DataBase Reference | 96568-04-6(CAS DataBase Reference) |
Hazard Codes | Xi | Risk Statements | 36/37/38 | Safety Statements | 26-36-37/39 | WGK Germany | 3 | Hazard Note | Irritant | HS Code | 29333990 |
| Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate Usage And Synthesis |
Chemical Properties | Off-White Solid | Uses | Enoxacin intermediate. | General Description | Ethyl 2,6-dichloro-5-fluoro-β-oxo-3-pyridinepropionate is a β-keto ester. |
| Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate Preparation Products And Raw materials |
Raw materials | Propanedioic acid, 2-[(2,6-dichloro-5-fluoro-3-pyridinyl)carbonyl]-, 1,3-diethyl ester-->Diethyl Ethoxymagnesiomalonate-->2,6-DICHLORO-5-FLUORONICOTINOYL CHLORIDE-->ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate-->2,6-Dichloro-5-fluoronicotinic acid-->2,6-Dihydroxy-5-fluoro-3-cyanopyridine-->2,6-DICHLORO-5-FLUORONICOTINAMIDE-->2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile-->Ethyl potassium malonate-->Ethyl hydrogen malonate | Preparation Products | Ethyl-2-(2,6-dichlor-5-fluorpyridin-3-carbonyl)-3-(2,4-difluorphenylamino)-acrylat |
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