Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:ReMaceMide hydrochloride;2-AMino-N-(1-Methyl-1,2-diphenylethyl)acetaMidehydrochloride CAS:111686-79-4 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Basic information |
Product Name: | 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE | Synonyms: | REMACEMIDE HYDROCHLORIDE;2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE;RemacemideHCl;2-AMino-N-(1,2-diphenylpropan-2-yl)acetaMide hydrochloride;2-amino-n-(1-methyl-1,2-diphenylethyl)-,monohydrochloride,(+-)-acetamid;2-diphenylethyl)acetamidemonohydrochloride(+-)-2-amino-n-(1-methyl-;fpl12924aa;pr934-423a | CAS: | 111686-79-4 | MF: | C17H21ClN2O | MW: | 304.82 | EINECS: | | Product Categories: | | Mol File: | 111686-79-4.mol | |
| 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Chemical Properties |
Melting point | 253-254° | storage temp. | room temp | solubility | H2O: >10mg/mL | form | powder | color | white to beige | Water Solubility | Soluble to 100 mM in water |
Hazard Codes | Xn,N | Risk Statements | 22-41-50/53 | Safety Statements | 26-39-45-60-61 | RIDADR | UN 3077 9 / PGIII | WGK Germany | 3 | RTECS | AB4349500 | Toxicity | LD50 (calculated as base) in rats (mg/kg): ~50 i.v., ~900 orally (Muir, Palmer) |
| 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Usage And Synthesis |
Uses | Anticonvulsant (neuroprotective). | Biological Activity | Non-competitive NMDA receptor antagonist; blocks ion channel and allosteric modulatory site (IC 50 = 8-68 mM). Anticonvulsant in vivo and metabolizes to a more potent desglycine analog. Weakly blocks voltage-dependent Na + channels (IC 50 = 161 mM). | Biochem/physiol Actions | Remacemide HCl is a low affinity NMDA antagonist with anticonvulsant properties. Remacemide also been shown to block voltage-dependent sodium channels. |
| 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Preparation Products And Raw materials |
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