对羟基苯乙烯
中文名称 | 对羟基苯乙烯 |
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中文同义词 | 4-乙烯基苯酚 1G;4-乙烯基苯酚, 10% 丙二醇溶液;4-羟基苯乙烯;4-乙烯基苯酚;4-乙烯基苯酚, MIN 10% 丙二醇溶液;4-乙烯基苯酚, 大约为10%丙二醇溶液;4-乙烯苯酚;4-乙烯基苯酚, 大约为丙二醇溶液 |
英文名称 | 4-Vinylphenol |
英文同义词 | 4-Vinylphenol solution 10 wt. % in propylene glycol;4-Vinylphenol,10%soln.inpropyleneglycol;PARA-VINYLPHENOL;4-Vinylphenol in 10% sol. Propylene glycol;4-VINYLPHENOL (10% SOLUTION IN PROPYLENE GLYCOL);4-VINYL PHENOL 10% IN PROPYLENE GLYCOL;p-Oxystyrene;Styrene-4-ol |
CAS号 | 2628-17-3 |
分子式 | C8H8O |
分子量 | 120.15 |
EINECS号 | 220-103-6 |
相关类别 | 合成材料中间体;香精香料;化工原料;其他原料;化工;对羟基苯乙烯;光刻胶单体;Aromatic Phenols |
Mol文件 | 2628-17-3.mol |
结构式 | ![]() |
对羟基苯乙烯 性质
熔点 | 73 °C |
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沸点 | 228.85°C (estimate) |
密度 | 1.04 |
蒸气压 | 9.38hPa at 25℃ |
折射率 | 1.4440 |
FEMA | 3739 | P-VINYLPHENOL |
闪点 | >230 °F |
储存条件 | under inert gas (nitrogen or Argon) at 2-8°C |
溶解度 | 可溶于氯仿(少量)、DMSO(少量) |
形态 | 液体 |
酸度系数(pKa) | 9.95±0.26(Predicted) |
颜色 | 透明无色至橙色 |
气味 (Odor) | 0.01% 的丙二醇溶液。化学酚类味道 |
香型 | phenolic |
水溶解性 | Slightly miscible with water. |
敏感性 | Hygroscopic |
JECFA Number | 711 |
BRN | 506844 |
稳定性 | 感光 |
LogP | 2.3 at 25℃ |
CAS 数据库 | 2628-17-3(CAS DataBase Reference) |
NIST化学物质信息 | 4-hydroxystyrene(2628-17-3) |
EPA化学物质信息 | Phenol, 4-ethenyl- (2628-17-3) |
4-Vinylphenol (12.5-200 µg/mL) significantly reduces cell viability in parental MDA-MB-231 cells, and the IC50 value is 109 µg/mL.
4-Vinylphenol (0.15 or 0.3 µg/mL; 3 days) reduces sphere‑formation and vimentin expression on CSCs in breast cancer.
4-Vinylphenol (50, 100 µg/mL; 72 hours) significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells.
4-Vinylphenol (100 µg/mL) significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis.