乳清酸锌二水合物
| 中文名称 | 乳清酸锌二水合物 |
|---|---|
| 中文同义词 | 乳清酸 锌盐 二水合物;乳清酸锌二水合物;乳清酸锌二水合物|乳清酸锌;乳清酸锌【乳清酸锌二水合物】 |
| 英文名称 | OROTIC ACID ZINC SALT DIHYDRATE |
| 英文同义词 | OROTIC ACID ZINC SALT DIHYDRATE;ZINC OROTATE;1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylicacizincsalt(2:1);zinc 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylate (1:2);Zincorotate2H2O;Orotic acid dihydrate zinc salt;Bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid)zinc salt;Bis(2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid) zinc salt |
| CAS号 | 68399-76-8 |
| 分子式 | C5H4N2O4Zn |
| 分子量 | 221.48 |
| EINECS号 | 269-988-0 |
| 相关类别 | 医药原料;营养增补剂;农用兽用原料;化工原料;Building Blocks;Heterocyclic Building Blocks;Pyrimidines;Heterocyclic Compounds |
| Mol文件 | 68399-76-8.mol |
| 结构式 |  |
乳清酸锌二水合物 性质
| 形态 | 固体 |
|---|---|
| 颜色 | 白色至米白色 |
| LogP | -0.928 (est) |
| EPA化学物质信息 | 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, zinc salt (2:1) (68399-76-8) |
Orotic acid (zinc)，一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。Orotic acid (zinc) 是尿素循环异常的常规新生儿筛查中的测量指标。Orotic acid (zinc) 可引起大鼠肝脂肪变性和肝肿大。
Orotic acid is found in milk and dairy products, and it is converted to uridine for use in the pyrimidine salvage pathway predominantly in liver, kidney and erythrocytes.
Orotic acid is a marker for measurement of urea cycle disorders (UCDs), including ornithine transcarbamylase deficiency (OTCD).
Orotic acid (1.0% addition to the diet; p.o. for 3-10 d) induces a development of fatty liver by day 7, and decreases purine/pyrimidine ratio of hepatic acid-soluble nucleotides by day 3.
安全信息
| 安全说明 | 22-24/25 |
|---|---|
| WGK Germany | 3 |