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| SB 269970 HYDROCHLORIDE Basic information |
Product Name: | SB 269970 HYDROCHLORIDE | Synonyms: | SB 269970 HYDROCHLORIDE;SB269970HCl;(2R)-1-[(3-HYDROXYPHENYL)SULFONYL]-2-[2-(4-METHYL-1-PIPERIDINYL)ETHYL]PYRROLIDINE HYDROCHLORIDE;Pyrrolidine, 1-((3-hydroxyphenyl)sulfonyl)-2-(2-(4-methyl-1-piperidinyl)ethyl)-, (R)-;(R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine;(R)-3-((2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)phenol;CS-776;SB-269970;SB 269970 | CAS: | 201038-74-6 | MF: | C18H28N2O3S | MW: | 352.49 | EINECS: | | Product Categories: | Serotonin receptor | Mol File: | 201038-74-6.mol | |
| SB 269970 HYDROCHLORIDE Chemical Properties |
Boiling point | 512.9±56.0 °C(Predicted) | density | 1.188 | storage temp. | Inert atmosphere,2-8°C | solubility | H2O: 22 mg/mL | form | solid | pka | 8.88±0.10(Predicted) |
| SB 269970 HYDROCHLORIDE Usage And Synthesis |
Uses | SB 269970 is a selective and potent SR-7 antagonist. | Definition | ChEBI: 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]phenol is a sulfonamide. | Biological Activity | Potent and selective 5-HT 7 receptor antagonist (pK i values are 8.9, 7.2 and 6.0 for 5-HT 7A , 5-HT 5A and 5-HT 1B and < 6.0 for 5-HT 1A , 5-HT 1D , 5-HT 1E , 5-HT 1F , 5-HT 2A , 5-HT 2B , 5-HT 2C , 5-HT 4 and 5-HT 6 receptors respectively). Brain penetrant in vivo . |
| SB 269970 HYDROCHLORIDE Preparation Products And Raw materials |
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