VUN65671 manufacturers
- VUN65671
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- $79.00 / 1mg
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2024-11-19
- CAS:2479465-67-1
- Min. Order:
- Purity: 99.85%
- Supply Ability: 10g
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| | VUN65671 Basic information |
| Product Name: | VUN65671 | | Synonyms: | VUN65671;EBOV/MARV-IN-1;Ebola and Marburg Entry Inhibitor;MARV,EBOV,virus,Filovirus,inhibit,Inhibitor,VUN-65671,VUN65671,Ebola,Marburg;N-(4-(4-Methylpiperidin-1-yl)-3-(trifluoromethyl)phenyl)-4-(morpholinomethyl)benzamide;Benzamide, N-[4-(4-methyl-1-piperidinyl)-3-(trifluoromethyl)phenyl]-4-(4-morpholinylmethyl)- | | CAS: | 2479465-67-1 | | MF: | C25H30F3N3O2 | | MW: | 461.52 | | EINECS: | | | Product Categories: | | | Mol File: | 2479465-67-1.mol |  |
| | VUN65671 Chemical Properties |
| Boiling point | 505.0±50.0 °C(Predicted) | | density | 1.242±0.06 g/cm3(Predicted) | | form | Solid | | pka | 12.89±0.70(Predicted) | | color | White to off-white |
| | VUN65671 Usage And Synthesis |
| Uses | EBOV/MARV-IN-1 is a potent inhibitor of Ebola virus (EBOV) and Marburg virus (MARV), with broad-spectrum activity (EC50=0.31, and 0.82 μM, respectively) and low cytotoxicity (SI>100) in HeLa cells[1]. | | IC 50 | EBOV; MARV | | References | [1] Gaisina IN, et, al. Discovery and Structural Optimization of 4-(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections. J Med Chem. 2020 Jul 9;63(13):7211-7225. DOI:10.1021/acs.jmedchem.0c00463 |
| | VUN65671 Preparation Products And Raw materials |
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