|
|
| | 4-Chloro-6,7-dimethoxyquinazoline Basic information |
| | 4-Chloro-6,7-dimethoxyquinazoline Chemical Properties |
| Melting point | 185 °C | | Boiling point | 345.5±37.0 °C(Predicted) | | density | 1.321±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 0.77±0.30(Predicted) | | color | White to Yellow | | Water Solubility | Insoluble in water. | | InChI | InChI=1S/C10H9ClN2O2/c1-14-8-3-6-7(4-9(8)15-2)12-5-13-10(6)11/h3-5H,1-2H3 | | InChIKey | LLLHRNQLGUOJHP-UHFFFAOYSA-N | | SMILES | N1=C2C(C=C(OC)C(OC)=C2)=C(Cl)N=C1 | | CAS DataBase Reference | 13790-39-1(CAS DataBase Reference) |
| | 4-Chloro-6,7-dimethoxyquinazoline Usage And Synthesis |
| Uses | A useful synthetic intermediate in the preparation of epidermal growth factors. | | Uses | 4-Chloro-6,7-dimethoxyquinazoline is a useful synthetic intermediate in the preparation of epidermal growth factors |
| | 4-Chloro-6,7-dimethoxyquinazoline Preparation Products And Raw materials |
| Raw materials | ETHYL 4,5-DIMETHOXY-2-NITROBENZOATE-->2-Amino-4,5-dimethoxybenzoic acid-->ETHYL 2-AMINO-4,5-DIMETHOXYBENZOATE-->6,7-Dimethoxy-3,4-dihydroquinazoline-4-one-->ETHYL 3,4-DIMETHOXYBENZOATE-->Methyl 2-amino-4,5-dimethoxybenzoate-->6-Nitroveratraldehyde-->3,4-DIMETHOXY-6-NITROBENZAMIDE-->4,5-Dimethoxy-2-nitrobenzoic acid-->2-AMINO-4,5-DIMETHOXYBENZAMIDE-->Veratraldehyde | | Preparation Products | 6-Quinazolinol, 4-chloro-7-methoxy--->N-(3-iodophenyl)-6,7-dimethoxyquinazolin-4-amine-->CEP-32496 (free base)-->JAK3 INHIBITOR I |
|