| Company Name: |
Guangzhou Isun Pharmaceutical Co., Ltd
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| Tel: |
020-39119399 18927568969 |
| Email: |
isunpharm@qq.com |
| Products Intro: |
Product Name:ReveroMycin A
CAS:134615-37-5
Purity:>=98% (HPLC), solid Package:25Mg; 1g; 100g; 500g
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| Company Name: |
Alfa Chemistry
|
| Tel: |
1-516-6625404 |
| Email: |
support@alfa-chemistry.com |
| Products Intro: |
Product Name:Reveromycin A
CAS:134615-37-5
Purity:99% Package:1g;10g;100g;1KG;5KG
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| | REVEROMYCIN A Basic information |
| Product Name: | REVEROMYCIN A | | Synonyms: | REVEROMYCIN A;ZESGNAJSBDILTB-OXVOKJAASA-N;Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester | | CAS: | 134615-37-5 | | MF: | C36H52O11 | | MW: | 660.79 | | EINECS: | | | Product Categories: | Epidermal Growth Factor Receptor (EGFR)Antibiotics;Interferes with Protein Synthesis;Antibiotics;Antibiotics A to;Antibiotics by Application;Antibiotics N-SAntibiotics;AntifungalAntibiotics;Mechanism of Action;Receptor Tyrosine Kinase Inhibitors;Spectrum of Activity;Antineoplastic and Immunosuppressive AntibioticsReceptor Tyrosine Kinase Biology | | Mol File: | 134615-37-5.mol |  |
| | REVEROMYCIN A Chemical Properties |
| Boiling point | 849.0±65.0 °C(Predicted) | | density | 1.21±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMF: soluble | | form | solid | | pka | 4.36±0.17(Predicted) | | color | tan |
| | REVEROMYCIN A Usage And Synthesis |
| Uses | Reveromycin A is a spiroketal antibiotic inhibitor of EGF mitogenic activity. Inhibits the signal transduction of the epidermal growth factor. May be used | | Uses | Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of EGF. Reveromycin A is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Reveromycin A displays antiproliferative behaviour against human cell lines KB and K562, as well as potent antifungal activity. More recently it has been shown to induce apoptosis in osteoclasts thus inhibiting bone resorption. |
| | REVEROMYCIN A Preparation Products And Raw materials |
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