- GALANTHAMINONE
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- $35.00 / 1kg
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2024-04-20
- CAS:510-77-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- GALANTHAMINONE
-
- $2.00 / 1KG
-
2020-01-08
- CAS:510-77-0
- Min. Order: 1g
- Purity: 98%MIN
- Supply Ability: ASK
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| GALANTHAMINONE Basic information |
Product Name: | GALANTHAMINONE | Synonyms: | GALANTHAMINONE;(4aS;8aS)-;(4aS,8aS)-4a,5,9,10,11,12-Hexahydro-3-Methoxy-11-Methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one;GalantaMine interMediate ((-)-Narwedine);GalantaMinone (GalantaMine IMpurity A);6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-one,4a,5,9,10,11,12-hexahydro-3-Methoxy-11-Methyl-, (4aS,8aS)-;Galanthaminone
Narwedine | CAS: | 510-77-0 | MF: | C17H19NO3 | MW: | 285.34 | EINECS: | | Product Categories: | raw materials;Various Metabolites and Impurities;Heterocycles;Intermediates & Fine Chemicals;Metabolites;Pharmaceuticals | Mol File: | 510-77-0.mol | ![GALANTHAMINONE Structure](CAS/GIF/510-77-0.gif) |
| GALANTHAMINONE Chemical Properties |
Melting point | 175-180°C (dec.) | Boiling point | 397.4±42.0 °C(Predicted) | density | 1.28±0.1 g/cm3(Predicted) | storage temp. | Sealed in dry,2-8°C | solubility | DMSO : 10 mg/mL (35.05 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) | form | Cryst. | pka | 7.84±0.20(Predicted) | color | White to off-white |
| GALANTHAMINONE Usage And Synthesis |
Description | This alkaloid occurs in several families of the Amaryllidaceae and is obtained as
colourless prisms when crystallized from Me2CO. It is dextrorotatory with
[α]25D
+ 100° (c 0.2, CHC13). It forms a crystalline picrate, m.p. 123°C; a
methiodide, m.p. 195-6°C and a semicarbazone, indicative of a keto group, m.p.
240-1 °c (dec.). | Chemical Properties | White to Off-White | Uses | A metabolite of Galanthamine, a selective acetylcholinesterase inhibitor | Uses | Narwedine is the biogenetic precursor of galanthamine, has been studied as a respiratory stimulator. It increases the amplitude and decreases the frequency of cardiac contractions and would therefore be of value in reducing blood loss during surgery. It also inhibits the action of narcotics and hypnotics, and increases the analgesic effect of morphine as well as the pharmacological effects of caffeine, carbazole, arecoline, and nicotine. | Definition | ChEBI: Narwedine is a benzazepine. | target | AChR | IL Receptor | References | Boit, Dapke, Beitner., Chem. Ber., 90,2197 (1957) |
| GALANTHAMINONE Preparation Products And Raw materials |
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