- Albuterol sulfate
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- $10.00 / 1ASSAYS
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2024-11-25
- CAS:51022-70-9
- Min. Order: 1ASSAYS
- Purity: 99%
- Supply Ability: 10 ton
- Salbutamol hemisulfate
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- $97.00 / 500mg
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2024-11-19
- CAS:51022-70-9
- Min. Order:
- Purity: 99.35%
- Supply Ability: 10g
- Albuterol sulfate
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- $2380.00 / 1KG
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2024-11-14
- CAS:51022-70-9
- Min. Order: 1Kg/Bag
- Purity: 98%
- Supply Ability: 1000KG
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| | Albuterol sulfate Basic information |
| | Albuterol sulfate Chemical Properties |
| Melting point | 180 °C | | Fp | 250 °C | | storage temp. | 2-8°C | | solubility | 1 M NaOH: soluble50 mg/ml, clear to slightly hazy, yellow-green | | form | Solid | | color | White | | Water Solubility | Soluble in water and 1M sodium hydroxide (50 mg/ml). | | Merck | 216 | | BCS Class | 1 | | InChI | InChI=1S/C13H21NO3.H2O4S/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4) | | InChIKey | OVICLFZZVQVVFT-UHFFFAOYSA-N | | SMILES | CC(C)(NCC(O)C1C=CC(O)=C(CO)C=1)C.S(O)(O)(=O)=O | | CAS DataBase Reference | 51022-70-9(CAS DataBase Reference) |
| Hazard Codes | Xn,Xi | | Risk Statements | 43-22 | | Safety Statements | 36/37-36 | | RIDADR | 2811 | | WGK Germany | 3 | | RTECS | ZE4400000 | | HS Code | 29225090 |
| | Albuterol sulfate Usage And Synthesis |
| Description | Albuterol sulfate (Brand name: PROVENTIL® HFA) is the sulfate form of albuterol which is also known as salbutamol. It is a kind of short-acting, selective beta2-adrenergic receptor agonist being capable of opening up the medium and large airways in the lungs. It is mainly used for the treatment of bronchospasm (induced by bronchial asthma or exercise) as well as chronic obstructive pulmonary disease (COPD). Albuterol sulfate takes effects through directly biding to the beta (2)-adrenergic receptors in the lung and causing relaxation of bronchial smooth muscles. This relaxation is mediated by its effect of stimulating cAMP production through activating adenylate cyclase, further inhibiting the phosphorylation of myosin and lowering the intracellular calcium level. Albuterol sulfate can also be used to treat acute hyperkalemia of the blood. | | Chemical Properties | Albuterol sulfate is a white or practically white powder, freely soluble in water and slightly soluble in ethanol. | | Uses | Albuterol Sulfate belongs to a class of bronchodilator drugs called β2-adrenoceptor agonists. It is a prescription medicine used to treat symptoms of bronchospasm. Albuterol Sulfate may be used alone or with other medications. | | Definition | ChEBI: Albuterol sulfate is an ethanolamine sulfate salt. It is functionally related to an albuterol. | | Brand name | Accuneb (Dey); Proair (IVAX); Proventil
(Schering); Ventolin (GlaxoSmithKline); Volmax (Muro);
Vospire (Odyssey). | | General Description | Albuterol belongs to the class of medicines known as bronchodilators. It is also called a short-acting beta-agonist (SABA). | | Biological Activity | Non-selective β -adrenergic agonist, more potent at β 2 than β 1 receptors. | | Veterinary Drugs and Treatments | Albuterol is used principally in dogs and cats for its effects on bronchial
smooth muscle to alleviate bronchospasm or cough. It is also
used in horses as a bronchodilator. | | storage | Store at RT | | Mode of action | Albuterol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction. | | References | https://en.wikipedia.org/wiki/Salbutamol
https://www.drugbank.ca/drugs/DB01001
http://www.rxlist.com/albuterol-sulfate-drug/indications-dosage.htm |
| | Albuterol sulfate Preparation Products And Raw materials |
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