D-谷氨酸
中文名称 | D-谷氨酸 |
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中文同义词 | D-谷氨酸(试剂);D-麸胺酸;D-2-氨基戊二酸;D-麸氨酸;D-麸质酸;D-Α-氨基戊二酸,D-Α-AMINOPENTANEDIOIC ACID;D-谷氨酸, 99+%;D-谷氨酸/Α-氨基戊二酸 |
英文名称 | D(-)-Glutamic acid |
英文同义词 | (2R)-2-Aminoglutaric acid;D-α-AMinoglutaric acid;D-1-AMinopropane-1,3-dicarboxylic acid;D(-)-GlutaMic acid, 99+% 25GR;D(-)-GlutaMic acid, 99+% 5GR;(2R)-GlutaMic Acid;NSC 77686;D-Glutaminic acid |
CAS号 | 6893-26-1 |
分子式 | C5H9NO4 |
分子量 | 147.13 |
EINECS号 | 230-000-8 |
相关类别 | 中间体;医药原料;天然氨基酸极其衍生物;氨基酸衍生物;氨基酸及其衍生物;生化试剂;生物化学品;氨基酸;化学生物学;植物提取物;氨基酸类;其他生化试剂;医药中间体;保护氨基酸;非天然氨基酸;Amino ACIDS SERIES;Glutamate receptor;amino acid;中药对照品;生化试剂-氨基酸类;化学试剂;有机原料;医用原料;原料;生化研究试剂;生化试剂-氨基酸;标准品;有机合成原料;D-氨基酸;有机中间体;有机化工原料;化工原料;原料药;通用生化试剂-氨基酸;对照品;Glutamic acid [Glu, E];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Nutritional Supplements;Amino Acids |
Mol文件 | 6893-26-1.mol |
结构式 | ![]() |
D-谷氨酸 性质
熔点 | 200-202 °C (subl.)(lit.) |
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比旋光度 | -31.3 º (c=10, 2 N HCl) |
沸点 | 267.21°C (rough estimate) |
密度 | 1.5380 |
折射率 | 1.4210 (estimate) |
储存条件 | Keep in dark place,Sealed in dry,Room Temperature |
溶解度 | 可微溶于水 |
形态 | 粉末 |
酸度系数(pKa) | pK1:2.162(+1);pK2:4.272(0);pK3:9.358(-1) (25°C) |
颜色 | 白色至类白色 |
水溶解性 | 7 g/L (20 ºC) |
Merck | 14,4469 |
BRN | 1723800 |
InChIKey | WHUUTDBJXJRKMK-GSVOUGTGSA-N |
LogP | -0.969 (est) |
CAS 数据库 | 6893-26-1(CAS DataBase Reference) |
NIST化学物质信息 | D-Glutamic acid(6893-26-1) |
EPA化学物质信息 | D-Glutamic acid (6893-26-1) |
Human Endogenous Metabolite
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Various d-amino acids, such as D-serine, D-aspartic acid (D-Asp), and D-glutamic acid (D-Glu) are widely found in mammals including human beings and they are now thought to be the candidates of novel physiologically active substances and/or biomarkers. D-[Asp/Glu] (4 mg/mL) inhibits IgE binding (75%) to peanuts while D-Glu, D-Asp has no inhibitory effect. IgE is specific for D-[Asp/Glu] and may have the potential for removing IgE or reducing IgE binding to peanut allergens.
D-glutamic acid is currently paid attention as a modulator of neuronal transmission and hormonal secretion. It is metabolized only by D-aspartate oxidase in mammals. After intraperitoneal injection, L-glutamate is catabolized via a-ketoglutarate, whereas D-glutamate is converted to n-pyrrolidone carboxylic acid. Carbon 2 of both D- and L-glutamate is converted in the cecum to the methyl carbon of acetate. Both rat liver and kidney catalyze the conversion of D-glutamic acid to n-pyrrolidone carboxylic acid.
安全信息
危险品标志 | Xi |
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危险类别码 | 36/37/38 |
安全说明 | 24/25-36-26 |
WGK Germany | 3 |
F | 10 |
TSCA | Yes |
海关编码 | 29224200 |
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