- Palbociclib Impurity 9
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- $0.00 / 10mg
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2024-09-20
- CAS:1013916-37-4
- Min. Order: 10mg
- Purity: 98%
- Supply Ability: 500mg
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| 2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Basic information |
Product Name: | 2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one | Synonyms: | 2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one;Pyrido[2,3-d]pyriMidin-7(8H)-one, 2-chloro-8-cyclopentyl-5-Methyl-;2-chloro-8-cyclopentyl-5-Me;Palbociclib Intermediate2;2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (For Palbociclib);2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one;2-chloro-8-cyclopentyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one;2-chloro-8-cyclopentyl-5-Methylpyrido[2 | CAS: | 1013916-37-4 | MF: | C13H14ClN3O | MW: | 263.72 | EINECS: | 800-066-8 | Product Categories: | Anticancer;1013916-37-4 | Mol File: | 1013916-37-4.mol | |
| 2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Chemical Properties |
Melting point | 176 - 178°C | Boiling point | 428.0±34.0 °C(Predicted) | density | 1.346±0.06 g/cm3(Predicted) | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | solubility | Chloroform (Slightly), Methanol (Slightly) | form | Solid | pka | 0.82±0.20(Predicted) | color | Yellow to Dark Yellow | Water Solubility | Slightly soluble in water. | InChI | InChI=1S/C13H14ClN3O/c1-8-6-11(18)17(9-4-2-3-5-9)12-10(8)7-15-13(14)16-12/h6-7,9H,2-5H2,1H3 | InChIKey | BSKNQSYIDZUXQT-UHFFFAOYSA-N | SMILES | C1(Cl)=NC=C2C(C)=CC(=O)N(C3CCCC3)C2=N1 |
| 2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Usage And Synthesis |
Description | 2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one is used as an intermediate for Palbociclib, a CDK 4/6 inhibitor used to treat patients with hormone receptor (HR)-positive, HER-2-negative advanced or metastatic (cancer that has spread) breast cancer. | Uses | 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one is used as pharmaceutical intermediate. |
| 2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Preparation Products And Raw materials |
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