ANXA2抑制剂多肽
中文名称 | ANXA2抑制剂多肽 |
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中文同义词 | ANXA2抑制剂多肽 |
英文名称 | LCKLSL |
英文同义词 | LCKLSL;L-Leucine, L-leucyl-L-cysteinyl-L-lysyl-L-leucyl-L-seryl- |
CAS号 | 533902-29-3 |
分子式 | C30H57N7O8S |
分子量 | 675.88 |
EINECS号 | |
相关类别 | 目录肽 |
Mol文件 | 533902-29-3.mol |
结构式 |
ANXA2抑制剂多肽 性质
沸点 | 1024.2±65.0 °C(Predicted) |
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密度 | 1.185±0.06 g/cm3(Predicted) |
酸度系数(pKa) | 3.30±0.10(Predicted) |
Annexin A2 (AnxA2)
In human retinal microvascular endothelial cells (RMVECs), treatment with LCKLSL (0-2 mg) inhibits the generation of plasmin and suppresses the VEGF-induced activity of tPA under hypoxic conditions.
Application of LCKLSL in two in vivo models (in chicken chorioallantoic membrane and murine Matrigel plug assays) of angiogenesis demonstrates suppression of the angiogenic responses. Treatment with the LCKLSL peptide significantly decreases the vascular length. At a dose of 5 μg/mL, the LCKLSL peptide significantly decreases the number of vascular branches, junctions and end-points.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2022/09/18 | HY-P2333 | ANXA2抑制剂多肽 LCKLSL | 533902-29-3 | 5mg | 2500元 |
2022/09/18 | HY-P2333 | ANXA2抑制剂多肽 LCKLSL | 533902-29-3 | 10mg | 4500元 |