| Company Name: |
MedChemexpress LLC
|
| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:Bunaftide
CAS:32421-46-8
Purity:200RMB/1mg Package:>98%
|
| Company Name: |
Shaanxi Dideu Newmaterial Co., Ltd.
|
| Tel: |
029-63373950 15353716720 |
| Email: |
1052@dideu.com |
| Products Intro: |
Product Name:Bunaftine
CAS:32421-46-8
Purity:98% Package:25kg
|
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.com |
| Products Intro: |
Product Name:Bunaftide
CAS:32421-46-8
|
|
| | bunaftine Basic information |
| Product Name: | bunaftine | | Synonyms: | Bunaphtide;Bunaphtine;Meregon;N-Butyl-N-[2-(diethylamino)ethyl]-1-naphthalenecarboxamide;Bunaftide;bunaftine;N-butyl-N-[2-(diethylamino)ethyl]naphthalene-1-carboxamide;1-Naphthalenecarboxamide, N-butyl-N-[2-(diethylamino)ethyl]- | | CAS: | 32421-46-8 | | MF: | C21H30N2O | | MW: | 326.48 | | EINECS: | 2510271 | | Product Categories: | | | Mol File: | 32421-46-8.mol |  |
| | bunaftine Chemical Properties |
| Boiling point | bp0.1 178° | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| Toxicity | LD50 i.p. in mice: 122 mg/kg (Giannini et al.) |
| | bunaftine Usage And Synthesis |
| Originator | Bunaftine,Malesci | | Definition | ChEBI: Bunaftine is a naphthalenecarboxamide. | | Manufacturing Process | Into a solution containing α-naphthoic acid chloride in benzene with agitation
and cooling for 0.5 h a benzene solution of N,N-diethylamine-ethyl-N'-(nbutyl)
amine is dropped. As the dropping is ended, the solution is kept under
agitation in a water bath for 3 h.
After cooling the benzene solution is extracted with 10% hydrochloric acid;
then the aqueous solution is saturated with potassium carbonate. The
separated oil is extracted with ether and, after drying on sodium sulfate, the
solvent is removed and the residue is vacuum distilled. So the N-(2-
diethylamino-ethyl)-N-(n-butyl)-1-naphthalenecarboxamide, boiling point
178°C/0.1 mm/Hg. | | Therapeutic Function | Antiarrhythmic |
| | bunaftine Preparation Products And Raw materials |
|