金石蚕苷
| 中文名称 | 金石蚕苷 |
|---|---|
| 中文同义词 | 金石蚕苷;金石蚕甙;金石蚕苷(标准品);金石蚕苷 (金石蚕甙);POLIUMOSIDE 金石蚕苷;金石蚕甙对照品,;金石蚕苷, 来源于广东紫珠;金石蚕苷(对照品) |
| 英文名称 | 2-(3,4-Dihydroxyphenyl)ethyl 3-O,6-O-bis(α-L-rhamnopyranosyl)-4-O-[(E)-3-(3,4-dihydroxyphenyl)propenoyl]-β-D-glucopyranoside |
| 英文同义词 | 2-(3,4-Dihydroxyphenyl)ethyl 3-O,6-O-bis(α-L-rhamnopyranosyl)-4-O-[(E)-3-(3,4-dihydroxyphenyl)propenoyl]-β-D-glucopyranoside;Poliumoside;6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-4-((3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)me;O-6-Deoxy-alpha-L-mannopyranosyl-(1-3)-O-[6-deoxy-alpha-L-mannopyranosyl-(1-6)]-beta-D-glucopyranoside 2-(3,4-dihydroxyphenyl)ethyl 4-[3-(3,4-dihydroxyphenyl)-2-propenoate];[6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-2-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxymethyl]oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate;Poliumoside, 98%, from Callicarpa kwangtungensis Chun;β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[6-deoxy-α-L-mannopyranosyl-(1→6)]-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate];[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-4-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate |
| CAS号 | 94079-81-9 |
| 分子式 | C35H46O19 |
| 分子量 | 770.73 |
| EINECS号 | |
| 相关类别 | 对照品;植提标准品;中药对照品;标准品;植物提取物;chemical reagent;pharmaceutical intermediate;phytochemical;精细化工;分析试剂标准品;标准品-对照品;标准品-中药标准品;标准品 -中药标准品;其它酚类;标准品，对照品;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
| Mol文件 | 94079-81-9.mol |
| 结构式 |  |
金石蚕苷 性质
| 沸点 | 1023.2±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.62 |
| 溶解度 | DMSO : 100 mg/mL (129.75 mM; 需要超声) 乙醇 : 50 mg/mL (64.87 mM; 需要超声) |
| 形态 | 粉末 |
| 酸度系数(pKa) | 9.31±0.10(Predicted) |
| 颜色 | 白色 |
Poliumoside对于晚期糖基化终产物的形成有显著抑制作用，IC50值为19.69 µM。 在大鼠晶状体醛糖还原酶测定试验中，发现 Poliumoside对rat lens aldose reductase(RLAR)表现出抑制作用，IC50值为8.47 µM。
药理药效:散瘀止血，消肿止痛。 叶:用于吐血，咯血，衄血，便血；外用治疗外伤出血。
| Target | Value |
|
RLAR
() | 8.47 μM |
Poliumoside inhibits AGE formation and RLAR, with IC
50
s of 19.69, and 8.47 μM, respectively.
Poliumoside (5-30 μM; 3 h) inhibits AAPH-induced hemolysis of rat red blood cells in vitro.
Poliumoside (12.5-100 μM; pretreated 2 h) inhibits the release of TNF-α and IL-6 in LPS-induced RAW 264.7 cells.
Poliumoside inhibits vessel dilation in larval zebrafish.
化学性质
类白色结晶粉末，溶于水，来源于广东紫珠。用途
金石蚕苷具有抗菌消炎抗病毒作用。用途
用于含量测定/鉴定/药理实验等。药理药效:散瘀止血，消肿止痛。 叶:用于吐血，咯血，衄血，便血；外用治疗外伤出血。
安全信息
| 海关编码 | 29389090 |
|---|
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/11/08 | HY-N0033 | Poliumoside | 5 mg | 1046元 | |
| 2024/11/08 | HY-N0033 | 金石蚕苷 Poliumoside | 94079-81-9 | 10mg | 1674元 |