H-ILE-ILE-GLY-LEU-MET-OH manufacturers
- β-Amyloid (31-35)
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- $33.00 / 1mg
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2024-11-19
- CAS:149385-65-9
- Min. Order:
- Purity: 100%
- Supply Ability: 10g
- Bate-Amyloid (31-35)
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- $0.10 / 1kg
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2024-08-27
- CAS:145389-65-9
- Min. Order: 1kg
- Purity: >98%
- Supply Ability: 20 tons
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| | H-ILE-ILE-GLY-LEU-MET-OH Basic information |
| Product Name: | H-ILE-ILE-GLY-LEU-MET-OH | | Synonyms: | Isoleucinyl-isoleucinyl-glycinyl-leucinyl-methionine;AMyloid b-Protein (31-35);AMYLOID BETA-PROTEIN (31-35);AMYLOID-BETA PROTEIN (31-35), HUMAN, MOUSE, RAT;BETA-AMYLOID (31-35);IIGLM;ILE-ILE-GLY-LEU-MET;H-ILE-ILE-GLY-LEU-MET-OH | | CAS: | 149385-65-9 | | MF: | C25H47N5O6S | | MW: | 545.74 | | EINECS: | | | Product Categories: | peptide | | Mol File: | 149385-65-9.mol |  |
| | H-ILE-ILE-GLY-LEU-MET-OH Chemical Properties |
| Boiling point | 866.4±65.0 °C(Predicted) | | density | 1.137±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | Soluble in DMSO | | pka | 3.24±0.10(Predicted) | | form | Solid | | color | White to off-white | | Sequence | H-Ile-Ile-Gly-Leu-Met-OH |
| | H-ILE-ILE-GLY-LEU-MET-OH Usage And Synthesis |
| Uses | β-Amyloid (31-35) is the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity. | | References | [1] Milton NG, et al. The amyloid-beta peptide binds to cyclin B1 and increases human cyclin-dependent kinase-1 activity. Neurosci Lett. 2002 Apr 5;322(2):131-3. DOI:10.1016/s0304-3940(02)00081-2
[2] Misiti F, et al. Fragment 31-35 of beta-amyloid peptide induces neurodegeneration in rat cerebellar granule cells via bax gene expression and caspase-3 activation. A crucial role for the redox state of methionine-35 residue. Neurochem Int. 2006 Oct;49(5):525-32. DOI:10.1016/j.neuint.2006.03.014
[3] M Jesús Pérez de Vega, et al. Synthesis and biological properties of beta-turned Abeta(31-35) constrained analogues. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2078-82. DOI:10.1016/j.bmcl.2008.01.092 |
| | H-ILE-ILE-GLY-LEU-MET-OH Preparation Products And Raw materials |
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