- Mannose Triflate
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- $0.00 / 1G
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2024-07-25
- CAS:92051-23-5
- Min. Order: 1G
- Purity: 98%min
- Supply Ability: 30kg/month
- TATM
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- $50.00 / 1kg
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2024-05-10
- CAS:92051-23-5
- Min. Order: 10kg
- Purity: 0.99
- Supply Ability: 20tons
- TATM
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- $6.00 / 1KG
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2024-03-29
- CAS:92051-23-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | Mannose Triflate Basic information |
| Product Name: | Mannose Triflate | | Synonyms: | MANNOSE TRIFLATE F;1,3,4,6-Tetraacetate 2-(trifluoromethanesulfonate) -D-Mannopyranose;tetraacetyltrifluoromethanesulfonyl-beta-D-mannopyranose;Mannose triflate, TATM, 1,3,4,6-Tetra-O-acetyl-2-O-trifluoromethanesulfonyl-β-D-mannopyranose;1-O,3-O,4-O,6-O-Tetraacetyl-2-O-(trifluoromethylsulfonyl)-β-D-mannopyranose;1-O,3-O,4-O,6-O-Tetraacetyl-2-O-trifluoromethanesulfonyl-β-D-mannopyranose;β-D-Mannopyranose 1,3,4,6-tetra-O-acetate 2-O-trifluoromethanesulfonate Mannose triflate;1,3,4,6-Tetra-O-acetyl-2-O-trifluoromethylsulfonyl-β-D-mannopyranose | | CAS: | 92051-23-5 | | MF: | C15H19F3O12S | | MW: | 480.36 | | EINECS: | 200-001-8 | | Product Categories: | FDG Chemicals;Biochemistry;chiral;Carbohydrates & Derivatives;Intermediates & Fine Chemicals;Labeling and Diagnostics Reagents;Pharmaceuticals;O-Substituted Sugars;Sugars | | Mol File: | 92051-23-5.mol |  |
| | Mannose Triflate Chemical Properties |
| Melting point | 118-122 °C | | alpha | [α]D20 -14～-17゜(c=1,CHCl3) | | Boiling point | 481.6±45.0 °C(Predicted) | | density | 1.50±0.1 g/cm3(Predicted) | | refractive index | -16 ° (C=1, CHCl3) | | storage temp. | -20°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Solid | | color | White to Off-White | | optical activity | [α]22/D -16°, c = 1 in chloroform | | BRN | 4341413 | | InChI | InChI=1/C15H19F3O12S/c1-6(19)25-5-10-11(26-7(2)20)12(27-8(3)21)13(14(29-10)28-9(4)22)30-31(23,24)15(16,17)18/h10-14H,5H2,1-4H3/t10-,11-,12+,13+,14-/s3 | | InChIKey | OIBDVHSTOUGZTJ-UBBZJQTNNA-N | | SMILES | [C@H]1(OC(=O)C)[C@H](OC(=O)C)[C@H](O[C@@H](OC(=O)C)[C@H]1OS(=O)(=O)C(F)(F)F)COC(=O)C |&1:0,5,10,12,17,r| |
| Hazard Codes | Xi | | Safety Statements | 24/25 | | WGK Germany | 3 | | F | 10-21 | | HS Code | 29329990 |
| | Mannose Triflate Usage And Synthesis |
| Description | Mannose triflate is a glucose analog. Mannose triflate is a well-known precursor for 18F-FDG synthesis for PET applications. 18F-FDG is an imaging technique for cancer.
| | Physical properties | White to off-white powder or crystal | | Uses | 1,3,4,6-Tetra-O-acetyl-2-O-trifluoromethanesulfonyl-beta-D-mannopyranose is a radiolabelled pharmaceutical preparation for diagnostic aims used in positron emission tomography. | | Preparation |
The tetraacetyl mannose (1.8 g, 5 mmol) was dissolved in anhydrous CH2Cl2(14 mL) containing dry pyridine (0.9 mL, 11 mmol). This solution was cooled to -15°C, and trifluoromethanesulfonic anhydride (triflic anhydride) (0.9 mL, 5.2 mmol) was added dropwise over 25 min under a nitrogen atmosphere with vigorous stirring. The mixture was then allowed to reach room temperature overnight. The reaction mixture was successively washed with ice-cold saturated aqueous NaHCO3(50 mL) and water (50 mL). The organic layer was dried over anhydrous Na2SO4, filtered, and concentrated on a rotary evaporator.2-Tf-O-AcManwas isolated by column chromatography on silica with hexane :EtOAc=1: 1 as the eluant as white solid Mannose triflate(1.4 g, 56percent).
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| | Mannose Triflate Preparation Products And Raw materials |
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