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Sichuan Wei Keqi Biological Technology Co., Ltd.
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Products Intro: |
Product Name:Thalidomide-NH-C6-NH2TFA CAS:2093386-51-5 Purity:98% Package:5mg;10mg;20mg;50mg;100mg;200mg;500mg;1g
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Thalidomide-NH-C6-NH2 TFA manufacturers
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| Thalidomide-NH-C6-NH2 TFA Basic information |
Product Name: | Thalidomide-NH-C6-NH2 TFA | Synonyms: | Thalidomide-NH-C6-NH2 TFA;Pomalidomide Related Compound 11 Triflate;4-((6-Aminohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate | CAS: | 2093386-51-5 | MF: | C21H25F3N4O6 | MW: | 486.45 | EINECS: | | Product Categories: | | Mol File: | 2093386-51-5.mol | |
| Thalidomide-NH-C6-NH2 TFA Chemical Properties |
solubility | Soluble in DMSO | form | Solid | color | Light yellow to yellow |
| Thalidomide-NH-C6-NH2 TFA Usage And Synthesis |
Biological Activity | Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. | References | [1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163. |
| Thalidomide-NH-C6-NH2 TFA Preparation Products And Raw materials |
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