Thalidomide-NH-C6-NH2 TFA

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Company Name:	Zhengzhou Alfa Chemical Co.,Ltd
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Products Intro:	CAS:2093386-51-5 Purity:95% Min. Package:100g; 500g; 1kg; 25kg;bulk package

Company Name:	TargetMol Chemicals Inc.
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Products Intro:	Product Name:Thalidomide-NH-C6-NH2 TFA CAS:2093386-51-5 Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	TargetMol Chemicals Inc.
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Products Intro:	Product Name:Thalidomide-NH-C6-NH2 TFA CAS:2093386-51-5 Package:5mg;98USD\|2mg;61USD

Company Name:	Sichuan Wei Keqi Biological Technology Co., Ltd.
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Products Intro:	Product Name:Thalidomide-NH-C6-NH2TFA CAS:2093386-51-5 Purity:98% Package:5mg；10mg；20mg；50mg；100mg；200mg；500mg；1g

Company Name:	Jilin Province Woda Biotechnology Co., Ltd.
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Products Intro:	Product Name:Thalidomide-NH-C6-NH2 TFA CAS:2093386-51-5 Purity:99% HPLC Package:1克;5克;

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Thalidomide-NH-C6-NH2 TFA Basic information

Product Name:	Thalidomide-NH-C6-NH2 TFA
Synonyms:	Thalidomide-NH-C6-NH2 TFA;Pomalidomide Related Compound 11 Triflate;4-((6-Aminohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate
CAS:	2093386-51-5
MF:	C21H25F3N4O6
MW:	486.45
EINECS:
Product Categories:
Mol File:	2093386-51-5.mol

Thalidomide-NH-C6-NH2 TFA Chemical Properties

Safety Information

MSDS Information

Thalidomide-NH-C6-NH2 TFA Usage And Synthesis

Uses	Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Biological Activity	Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
IC 50	Cereblon
References	[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

Thalidomide-NH-C6-NH2 TFA Preparation Products And Raw materials

Tag:Thalidomide-NH-C6-NH2 TFA(2093386-51-5) Related Product Information

Thalidomide-O-amido-C2-NH2 4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy)isoindoline-1,3-dione -alkylC5-amine 4-[(6-Aminohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl E3 ligase Ligand-Linker Conjugates 15 Thalidomide-O-amido-C2-NH2 Thalidomide-NH-C4-NH-Boc Thalidomide-NH-C4-NH2 TFA Thalidomide-NH-PEG2-C2-NH2 hydrochloride Thalidomide-NH-PEG2-C2-NH2 (TFA) 5-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, Pentanoic acid, 5-[[2-(2,6-dioxo-3-piperidinyl)- 2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]- 1H-Isoindole-1,3(2H)-dione, 4-(3-aminopropoxy)-2-(2,6-dioxo-3-piperidinyl)- 5-[(8-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, 1H-Isoindole-1,3(2H)-dione, 4-(2-aminoethoxy)-2-(2,6-dioxo-3-piperidinyl)- β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- 5-[(5-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione,

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