| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:AG 527
CAS:133550-32-0
Purity:>98% Package:25mg
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| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:Tyrphostin B44, (-) enantioMer;(R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenaMide
CAS:133550-32-0
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Wuhan Chemwish Technology Co., Ltd
|
| Tel: |
86-027-67849912 |
| Email: |
sales@chemwish.com |
| Products Intro: |
Product Name:AG527
CAS:133550-32-0
Purity:98% Package:1g;5g;25g;50g;100g;500g
|
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| | TYRPHOSTIN B44 Basic information |
| Product Name: | TYRPHOSTIN B44 | | Synonyms: | (R)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE;(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE;(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE;TYRPHOSTIN AG 527;TYRPHOSTIN B44;TYRPHOSTIN B44(-);TRYPHOSTIN AG 527;AG 527 | | CAS: | 133550-32-0 | | MF: | C18H16N2O3 | | MW: | 308.33 | | EINECS: | | | Product Categories: | Intracellular Signaling;Protein Kinase | | Mol File: | 133550-32-0.mol |  |
| | TYRPHOSTIN B44 Chemical Properties |
| Boiling point | 603.0±55.0 °C(Predicted) | | density | 1.299±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMSO or ethanol: soluble | | form | Yellow solid. | | pka | 8.81±0.10(Predicted) |
| | TYRPHOSTIN B44 Usage And Synthesis |
| Uses | Tyrphostin B44, (-) enantiomer is a potent inhibitor of (EGFR) kinase. | | Biological Activity | Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC 50 = 0.4 μ M), more active than the (+) enantiomer ((S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). Selective over ErbB2. |
| | TYRPHOSTIN B44 Preparation Products And Raw materials |
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