Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:Tyrphostin B44, (+) enantioMer;(S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenaMide CAS:133550-37-5 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
TCI (Shanghai) Development Co., Ltd.
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Tel: |
021-67121386 |
Email: |
Sales-CN@TCIchemicals.com |
Products Intro: |
Product Name:Tyrphostin AG 835 CAS:133550-37-5 Purity:98.0% LC Package:100MG,25MG
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| TYRPHOSTIN AG 835 Basic information |
Product Name: | TYRPHOSTIN AG 835 | Synonyms: | AG 835;ALPHA-CYANO-(+)-(S)-N-(ALPHA-PHENETHYL)-(3,4-DIHYDROXY)CINNAMIDE;(S)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE;(+)-(S)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE;TYRPHOSTIN B44, (+) ENANTIOMER;TYRPHOSTIN AG 835;TYRPHOSTIN B50;TYRPHOSTIN B50(+) | CAS: | 133550-37-5 | MF: | C18H16N2O3 | MW: | 308.33 | EINECS: | | Product Categories: | Protein Kinase | Mol File: | 133550-37-5.mol | ![TYRPHOSTIN AG 835 Structure](CAS/GIF/133550-37-5.gif) |
| TYRPHOSTIN AG 835 Chemical Properties |
Melting point | 146 °C | Boiling point | 603.0±55.0 °C(Predicted) | density | 1.299±0.06 g/cm3(Predicted) | storage temp. | −20°C | solubility | DMSO or ethanol: soluble | form | powder to crystal | pka | 8.81±0.10(Predicted) | color | Light yellow to Amber to Dark green |
Safety Statements | 22-24/25 | WGK Germany | 3 | HS Code | 2926.90.4801 |
| TYRPHOSTIN AG 835 Usage And Synthesis |
Uses | Tyrphostin B44, (+) enantiomer is an EGFR kinase inhibitor. | Biological Activity | Epidermal growth factor receptor (EGFR) kinase inhibitor (IC 50 = 0.86 μ M). Slightly less active than the (-) enantiomer ((R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). |
| TYRPHOSTIN AG 835 Preparation Products And Raw materials |
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