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| | BMS-986195 Basic information | | Uses |
| Product Name: | BMS-986195 | | Synonyms: | BMS-986195;CPD1640;1H-Indole-7-carboxamide, 5-fluoro-2,3-dimethyl-4-[(3S)-3-[(1-oxo-2-butyn-1-yl)amino]-1-piperidinyl]-;BMS-986195; BMS986195; BMS986195;(S)-4-(3-(but-2-ynamido)piperidin-1-yl)-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide;Branebrutinib (BMS-986195);BMS-986195 USP/EP/BP;Inhibitor,BMS-986195,Btk,inhibit,BMS 986195,Bruton tyrosine kinase,Branebrutinib | | CAS: | 1912445-55-6 | | MF: | C20H23FN4O2 | | MW: | 370.42 | | EINECS: | | | Product Categories: | | | Mol File: | 1912445-55-6.mol |  |
| | BMS-986195 Chemical Properties |
| density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:87.0(Max Conc. mg/mL);234.86(Max Conc. mM)
Ethanol:38.0(Max Conc. mg/mL);102.58(Max Conc. mM) | | form | A crystalline solid | | pka | 11.91±0.20(Predicted) | | color | White to off-white |
| | BMS-986195 Usage And Synthesis |
| Uses | Branebrutinib (BMS-986195) is a potent inhibitor of BTK with IC50 values of 0.1 nM, 0.9 nM, 1.5 nM, 5 nM for BTK, TEC, BMX, TXK, respectively. |
| | BMS-986195 Preparation Products And Raw materials |
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